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IV Training Practice Review Questions. USP/NF 797 requires that air sampling for high risk level areas be performed at least: Daily Weekly Monthly Annually.

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Presentation on theme: "IV Training Practice Review Questions. USP/NF 797 requires that air sampling for high risk level areas be performed at least: Daily Weekly Monthly Annually."— Presentation transcript:

1 IV Training Practice Review Questions

2 USP/NF 797 requires that air sampling for high risk level areas be performed at least: Daily Weekly Monthly Annually weekly

3 How often must work surfaces in the ISO Class 7 and 8 area buffer/clean rooms be cleaned? At least daily Every shift Every 8 hours PRN At least daily

4 Which of the following pharmacy areas should not contain sinks or floor drains according to USP/NF 797? Workroom Anteroom Clean room All of the above Clean room

5 The Buffer / Clean rooms should provide which of the following environments according to USP/NF 797? ISO class 6 ISO class 7 ISO class 8 None of the above ISO Class 7

6 Which is NOT a compounding example of a Low-Risk level Sterile Preparation? A single transfer from a sterile ampule using sterile supplies Measuring/mixing 2 manufactured products to prepare an admixture Measuring/mixing 3 manufactured products to prepare a nutritional preparation Measuring/mixing 4 manufactured products for TPN. Measuring/mixing 4 products

7 Which is a compounding example of a High- Risk level Sterile Preparation? Sterile ingredients are measured/mixed in nonsterile devices before sterilization. Dissolving nonsterile bulk drug and nutrient powders for solutions to be sterilized. TPN fluids prepared by automated device requiring multiple injections to a container. All of the above. Only A&B

8 How often must High-Risk level media fill testing be conducted by compounding personnel? At least monthly At least annually At least semiannually At least weekly At least semiannually

9 Which of the following components of a syringe must remain sterile? Tip Barrel Inner core of plunger All of the above Only A and C

10 Which gauge of needle would be used to draw up a thick substance such as Albumin? 14 gauge 18 gauge 21 gauge 23 gauge 14 gauge

11 Which of the following components of the Intravenous Administration Set is used to calculate the rate at which the solution is being infused? Spike Drip chamber Roll clamp Additive port Needle adaptor Drip chamber

12 The cover protecting the Intravenous Administration Set spike should not be removed outside of the hood prior to inserting it into the IV bag administration set port because it must remain sterile at all times. True False True

13 When preparing a TPN solution containing both phosphate and calcium type additives, _______ should be added first, then squeeze and agitate the additive port, flush by adding other drugs in between and then add ______ last. Calcium, phosphate Phosphate, calcium

14 There are various sizes of bacteria, but the average size of bacteria is 5 micron 13 micron 1 micron 20 micron None of the above 1 micron

15 Which of the following bacteria are so light in weight that they can stay suspended in air and be carried by air currents? Staphylococcus Streptococcus Proteus All of the above Only A and B

16 Alcohols have excellent in vitro germicidal activity against Gram-positive vegetative bacteria Gram-negative vegetative bacteria Multidrug-resistant pathogens Mycobacterium tuberculosis All of the above

17 Put the following gowning and gloving garb in the correct order, according to USP NF/797. Head and/or facial hair covers Nonshedding gown Shoe cover Sterile gloves Face mask B,D,A,E,C: shoe covers, head/hair covers, Face mask, gown, sterile gloves

18 The USP NF/797 states that when carts are being used they can NOT cross over clean zones unless they are cleaned and sanitized before returning to the clean room. True False True

19 If the blower on a laminar flow hood or barrier isolator is turned off, then only TWO persons can enter the buffer area for the purposes of turning on the blower and of sanitizing the work surface for a minimum of 30 minutes. True False

20 USP NF/797 requires that all surfaces of the direct compounding environment be first cleaned with _____, to remove any water soluble residues, then with ______, and wiped clean with a nonshedding wipe. Water for irrigation, Sterile 70% Isopropyl Alc. Sterile water, Purified 70% Isopropyl Alcohol Purified Water, Sterile 70% Isopropyl Alcohol Spring Water, 90% Isopropyl Alcohol Purified Water, Sterile 70% Isopropyl Alcohol

21 In which laminar airflow hood is the HEPA filter located at the back of the hood facing the preparer? Vertical airflow Horizontal airflow Biological safety cabinet Only A and C None of the above Horizontal airflow

22 In which Class of Biological Safety cabinet is the entire cabinet under negative pressure where operations are performed through attached gloves and the cabinet is entirely enclosed with gas tight construction? Class I Class II Class III None of the above Class III

23 In which type of Biological Safety cabinet is air not re-circulated, total exhaust? Type A Type B1 Type B2 Type B3 Type B2

24 When working in a horizontal laminar airflow hood, all manipulations should be performed at least ___ inches within the hood to prevent contamination of mixed air from the room

25 When working inside the vertical flow hood, all manipulations should be carried out at least ___ or more inches above the work surface area, because of where the HEPA filter is located

26 When using a contaminant barrier isolator to prepare cytotoxic or hazardous drugs, it should be under ______ pressure. Positive Negative

27 Which of the following drugs are used to treat cancer by substituting in or blocking the use of essential nutrients and enzymes? Mitotic Inhibitors Alkylating Agents Antimetabolites None of the above Antimetabolites

28 Which of the following drugs are considered the first anticancer drugs and work by binding to human DNA cells to stop their duplicating? Mitotic Inhibitors Alkylating Agents Antimetabolites None of the above Alkylating Agents

29 Although Vinblastine and Vincristine can both be used to treat solid tumors, lymphomas, and Hodgkins disease, only one of these can be used to treat Leukemia. Which is it? Vinblastine Vincristine Oncovin Both A and C Both B and C

30 Which of the following cancer drugs can be used to treat testicular cancer? Ifosfamide Etoposide Dactinomycin All of the above

31 Which of the following cancer drugs can be used to treat head, neck and lung cancer? Mitomycin Methotrexate Mithracin All of the above Only A and B

32 Match the cancer drugs with the correct cell cycle specific agent they act upon. Cytarabine Bleomycin Floxuridine Vinblastine A.G1 Phase, S Phase B.G2 Phase, M Phase C.M Phase D.S Phase D, B, A, C

33 Which of the following cytotoxic agents is considered a vascular irritant, not a vesicant? Mitomycin Mitoxantrone HCl Mechlorethamine HCl All of the above are vascular irritants. None of the above. Mitoxantrone HCl

34 OSHA recommends cleaning ____ time(s) using a detergent solution followed by water when cleaning up a small hazardous drug spill. One Two Three Four Three

35 Which of the following Cytotoxic drugs must be filtered? Alemtuzumab Asparaginase Aldesleukin Interleukin-2 Dactinomycin Daunorubian Citrate Liposomal Alemtuzumab

36 Which of the following solutions should Filgrastim (Neupogen) be mixed in? NS D5W Sterile Water All of the above D5W

37 Which of the following Cytotoxic agents should be mixed in a glass container? Docetaxel Doxorubicin Dacarbazine Dexrazoxane Docetaxel

38 Which of the following cytotoxic agents should be diluted with NaCl instead of D5W? Mechlorethamine Mitomycin Cladridine All of the above Only A and B All of the above

39 The USP NF/797 requires daily monitoring and documentation of refrigerators to ensure that the temperature remains between ______ degrees Celsius. 2 to 8 4 to 10 6 to 12 8 to to 16 2 to 8

40 The USP defines room temperature as © 8 to to to to to to 25

41 The USP 797 requires that any compounded sterile preparation which is exposed to temperatures exceeding 40 degrees Celsius for more than 4 hours should be discarded unless appropriate documentation or direct assay can confirm the preparation is stable. True Fals e True

42 The USP 797 requires that labeling for IV preparations which are shipped off-site contain which of the following? Clearly readable beyond use dates Storage instructions Instructions for disposal of out-of-date units All of the above are required. Only A and B are required. All of the above are required.

43 Which of the following IV Admixtures does NOT require filter tubing when dispensing? Albumin Amiodarone Fat Emulsion Mannitol Sodium Nitroprusside

44 Which of the following IV admixtures should NOT be refrigerated when dispensing? Acyclovir Dopamine Metronidazole All of the above Only A and C All of the above

45 Which of the following IV admixtures should be mixed in glass containers when dispensing? Hydrochloric Acid Nitroglycerin Amiodarone if infusion > 2 hours All of the above Only A and B All of the above

46 Which of the following injectables MUST be stored in the refrigerator? Amphoteracin B Atenolol Filgrastim All of the above must be refrigerated. Only A and C

47 Which of the following injectables should NOT be stored in the refrigerator? Vecuronium Bromide Ganciclovir Powder Polymixin B Sulfate All of the above Only B and C All of the above

48 The USP 797 divides contamination into 4 major categories. True False False; just 3 categories

49 Which of these would work for the sterilization AND depyrogenation process? Temp 160° Celsius for minutes Temp 170° Celsius for minutes Temp 180° Celsius for minutes Temp 230° Celsius for minutes

50 The Texas State Board of Pharmacy does NOT require which of these on the “Master Formulation Worksheet” for batched prepared sterile preparations. Formula, components, compounding directions Pharmacist and PT names / signatures Specific equipment used and a sample label Evaluation and testing requirements Sterilization methods and storage req. Pharmacist and PT names / signatures

51 Which of the following is NOT required on the label of a sterile pharmaceutical product by the Texas State Board of Pharmacy? Patient birth date Patient name Patient location Patient identification Patient birth date

52 Which of the following is NOT required by the USP 797 on labels and accessory labels for all compounded sterile preparations shipped off- site by a pharmacy? Clearly readable beyond-use dates Storage instructions Instructions for contacting the physician in case of emergency Instructions for disposal of out-of-date units Instructions for contacting the physician

53 Using multiple ampules to be transferred into one final sterile container is an example of: Immediate Use Risk Level Low Risk Level Medium Risk Level None of the Above Medium Risk Level

54 Only a single transfer from a sterile vial utilizing sterile supplies is an example of Immediate Use Risk Level Low Risk Level Medium Risk Level High Risk Level None of the Above Low Risk Level

55 Emergency Room Treatments, to be used within 1 hour, are an example of Immediate Use Risk Level Low Risk Level Medium Risk Level High Risk Level None of the Above Immediate Use Risk Level

56 Sterile ingredients measured /mixed with nonsterile devices before sterilization is performed is an example of Immediate Use Risk Level Low Risk Level Medium Risk Level High Risk Level None of the above High Risk Level

57 How many grams of Mannitol are needed to prepare 500 grams of a 10% (w/w) solution in water?

58 You need to prepare a 20% viscous Lidocaine solution. How many grams of Lidocaine will need to be dissolved in 500 ml of water to make this solution?

59 What is the percentage strength of a solution containing Benadryl 50 gm in 473 ml of liquid?

60 How many grams of Mannitol will you need to prepare 1 liter of a 20% solution?

61 How many grams of Epinephrine are needed to prepare 500 ml of a 0.01% Epinephrine solution?

62 In order to prepare 1 liter of 5% Hydrochloric Acid solution, how many ml’s of Hydrochloric Acid are required?

63 For the last question, how many ml’s of sterile water should be added to the Hydrochloric acid solution to prepare the 1 liter solution?

64 A 500 ml bag of D5NS infusing at 32 ml/hour will last for how many hours?

65 For the last question, how many bags will need to be sent in a 24 hour period?

66 You have Pitocin 40 units in D5W 500 ml to be infused over 4 hours. What is the rate in ml/hr the patient is receiving the Pitocin?

67 Order: D5LR infusing at 80 ml/hr. How many ml’s will be infused at the end of 24 hours?

68 What is the rate of infusion of Dopamine 250 mg in D5W 500 ml to be infused over 4 hours?


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