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The Germ Theory of Disease Alexander Fleming “One sometimes finds what one is not looking for.”

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Presentation on theme: "The Germ Theory of Disease Alexander Fleming “One sometimes finds what one is not looking for.”"— Presentation transcript:

1 The Germ Theory of Disease Alexander Fleming “One sometimes finds what one is not looking for.”

2 The Germ Theory of Disease Important early microbiologists helped to develop the Germ Theory – Anton Van Leeuwenhoek (1670’s) – Ignaz Semmelweis (1840’s) – Louis Pasteur (1860’s) – Joseph Lister (1860’s) – Robert Koch (1870’s) – Alexander Fleming (1920’s)

3 Alexander Fleming

4 Scottish Biologist and Pharmacologist Discovered the first antibiotic

5 Alexander Fleming Antibiotic =

6 Alexander Fleming World War I: worked as medical officer

7 Alexander Fleming Problems with antiseptics: – Work well on surfaces, but deep wounds are harder to treat – Kill bacteria indiscriminately

8 Alexander Fleming Began searching for more effective antiseptic – Discovered lysozyme » =

9 Alexander Fleming “ When I woke up just after dawn on September 28, 1928, I certainly didn’t plan to revolutionize all medicine by discovering the world’s first antibiotic, or bacteria killer. But I suppose that was exactly what I did”

10 Discovery of Penicillin Brilliant researcher, untidy laboratory Contaminated petri dish contained mold that was attacking staphylococci

11 Discovery of Penicillin Found that Penicillin could be used against:

12 Problems with Penicillin

13 Penicillin Fleming finally abandoned penicillin, but two scientists took up his research during World War II


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