2Defining Heart Failure Heart unable to supply enough oxygen-carrying blood to meet the metabolic needs of the bodyBegins with an injury to the myocardium that affects the ventricles’ ability to fill/eject bloodRemodeling occurs; process of dilation/hypertrophy of one or both of the ventricles
3Types of Heart FailureLow-output heart failure-Left ventricle unable to eject enough blood, due to weakness caused by MI, pulmonary hypertensionHigh-output heart failure-Volume of blood exceeds what ventricle can eject, resulting in back-up of blood and dilation of ventricle; causes: mitral valve regurgitation, aortic valve insufficiency, hyperthyroidism, anemia, hypervolemia
4Types, continuedBiventricular failure-Back-up pressure from failing left ventricle causes dilation/failure of right ventricleLeft ventricular systolic dysfunction-Heart muscle too weak to contract fullyLeft ventricular diastolic dysfunction-Left ventricle becomes stiff and can’t fill adequately
5CausesCoronary artery disease & hypertension responsible for 2/3 of heart failure casesRemaining cases caused by non-ischemic cardiomyopathy related to:• thyroid dysfunction• valvular heart disease• cardiotoxic substances: alcohol, cocaine, chemotherapy• idiopathic or unknown
6Heart Failure Stages: ACC/AHA Stage A: Patients are at risk for heart failure, but have no symptoms or structural changes; typically have diabetes, hypertension, coronary artery disease.Stage B: Patients have a documented structural heart change but no symptoms yet; may have hx of MI, valve regurgitation, left ventricular hypertrophy.Stage C: Patients with structural changes and symptoms.Stage D: Patients with refractory heart failure; may require mechanical or pharmaceutical support, a transplant, or end-of-life care.
7NYHA Classification System Class 1: Ordinary physical activity doesn’t cause undue fatigue, dyspnea, or anginal pain.Class II: Asymptomatic at rest, slight limitations of physical activity. Ordinary physical activity causes palpitations, dyspnea, & anginal pain.Class III: Marked limitations of physical activity, but asymptomatic at rest. Less-than-ordinary physical activity causes fatigue, palpitations, dyspnea, or anginal pain.Class IV: Patient unable to perform physical activity without discomfort, may have symptoms at rest. This patient will be considered for mechanical or pharmaceutical support, heart transplant or end-of-life care.
9Compensatory Mechanisms Cardiac output=stroke volume x heart rateOne of the body’s mechanisms to compensate is to release norepinephrine & epinephrine to increase HR, which increases cardiac output.Another mechanism is the renin-angiotensin-aldosterone system, which senses decreased blood volume to the kidneys and activates a series of events to increase fluid volume and blood pressure.
10More CompensationAnother mechanism is to increase stroke volume by increasing the amount of fluid in the bloodstream.Release of two amino acids: human atrial natriuretic peptide (hANP) & human brain natruiretic peptide (hBNP); both released by “stretch” receptors in the atria and ventricles, respectively, in response to increased blood volume; purpose: to lose excess fluid volume, which decreases BP and improves blood flow through the coronary arteries.
12DiagnosticsTransthoracic echocardiogram (TEE): Most common & effective diagnostic toolCoupled with Doppler flow studies, TEE can show atrial/ventricular hypertrophy, valve problems, where problem is located (inside or outside the heart), and when problem occurs (systole or diastole)12-lead ECG, chest X-ray, MRI, CT scanR & L heart catheterization
15Treatment, continued:Afterload-Deflation after blood leaves; determined by ventricular pressure, blood volume, & wall thickeningContractility-Contraction of the myocardium to force blood out of the heart
16Nursing Interventions Monitor vital signs/daily weightsInstruct patient about their medical therapyInstruct patient regarding sodium restrictionInstruct patient regarding positions of comfort (semi-Fowler’s)
17More Nursing Interventions Stress importance of contacting HCP about weight gain of 2 lbs or more/day or 5 lbs in a week or if awakened with dyspneaIf patient smokes, provide smoking cessation infoTeach caution using NSAIDs due to sodium retention, myocardial depression