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Dissolution Profiles of Non- Prescription Niacin & Niaspan Poon, Ivy, et al. Am J Health-Syst PharmVol 63 Nov 1, 2006.

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Presentation on theme: "Dissolution Profiles of Non- Prescription Niacin & Niaspan Poon, Ivy, et al. Am J Health-Syst PharmVol 63 Nov 1, 2006."— Presentation transcript:

1 Dissolution Profiles of Non- Prescription Niacin & Niaspan Poon, Ivy, et al. Am J Health-Syst PharmVol 63 Nov 1, 2006

2 Kinetics of Endur-acin (wax-matrix, extended-release nicotinic acid) Ivanofskaya E.A. et al. Khimiko–Farmatsevticheskii Zhurnal. Vol 32 No 5, 1998

3 Wax-Matrix ER Niacin Tolerability AUTHORDATEPATIENT #DROP-OUT Alderman19891014% Keenan19911503.7% Keenan19921583.4% Keenan1992988% Oganov1994695% Aronov1996894.5% Pasternak*1996448%* Ozerova199769? Kisseleva199940? Keenan20071202.5% Total938? Mean overall drop-out rate is 4.7% of niacin treated patients.


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