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Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation.

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Presentation on theme: "Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation."— Presentation transcript:

1 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Grants Overview Research Resources Catrina Codd BSc, MPH Research Manager

2 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Funding Trainees – up to $20,000 Staff Specialists – up to $50,000 Project Grants - Funding of up to $100,000 per year for up to 3 years. Program Grants - Funding up to $250,000/ year for up to 3 years. Leverage Funding of up to $50,000 per annum for up to 3 yrs

3 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Research Fellowship Scheme Research Fellowship Scheme - contribute to the salary costs –Short Research Fellowship (Full-time or Part-time) This is a month full-time (or month part- time) Maximum of AUS $150,000 per annum. –Research Fellowship (Full-time or Part-time) (research based Masters, Professional Doctorate, PhD, DrPH or MD). Maximum of AUS $150,000 per annum up to 3 years.

4 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Thinking In order for competent and innovative knowledge exploration to take place in parallel with conventional data gathering, it is important that creative and skilled reflection will count as original research in medical academe. Competent analytical thinking should be considered just as important and valuable to medicine as competent doing of traditional, empirical research. Getz L, Luise Kirkengen A, Hetlevik I. Too much doing and too little thinking in medical science! Scand J Prim Health Care. 2008;26(2):65-6. Free article at journal site – This article includes a quote from the 1915 Nobel laureate in physics William Bragg. In the middle of one of physics major paradigm shifts he is supposed to have said:Too much doing and too little thinking in medical science!Free article at journal site The important thing in science is not so much to obtain new facts as to discover new ways of thinking about them.

5 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Ask why? Ask what if?

6 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Work on Important Problems Ten simple rules for doing your best research, according to Hamming. Erren TC, Cullen P, Erren M, Bourne PE. PLoS Comput Biol Oct;3(10): Free article in PMC | at journalTen simple rules for doing your best research, according to Hamming.Free article in PMC | at journal Presentation title, Event name, Event date (edit by going to View>Header and Footer)

7 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Logistics Taylor DM, Practical Issues in the design and execution of an emergency medicine research study. Emergency Medicine (1999) Vol 11 Issue 3, Mentors – Published in your area? Mentors – both Emergency Medicine Research and Therapeutic Area Specialist Mentors – ACEM Researcher Database available via ACEM Members section >Members>Clinical Trials Group>Researcherswww.acem.org.au

8 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Office of Health and Medical Research – Qld Health Ethics Review & Governance National Statement on Ethical Conduct in Human ResearchNational Statement on Ethical Conduct in Human Research Australian Code for the Responsible Conduct of ResearchAustralian Code for the Responsible Conduct of Research Fellowships & Grants for Investing in People & Projects Intellectual property Commercialisation

9 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Mater Health Services Research-Ethics-Committee.aspxhttp://www.mater.org.au/Home/Research/Human- Research-Ethics-Committee.aspx Mater Medical Research Institute - Medical Research Institute -

10 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation University Research Divisions Griffith University - –Research support: James Cook University - –Research Services: –Assistance for grant applicants: –Checklist for a winning Grant: QUT - –Writing Grants - –Mentoring - UQ - –Burns, Trauma & Critical Care Research Centre Bond University - Presentation title, Event name, Event date (edit by going to View>Header and Footer)

11 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Logistics NATIONAL ADVICE SERVICE FOR RESEARCHERS comprehensive research site. Research Process Flowcharthttp://www.rddirect.org.uk/

12 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Resources Lessons from a Novice EMS Researcher Henry E. Wang, M.D., M.P.H. Assistant Professor, Department of Emergency Medicine University of Pittsburgh School of Medicine 59/Default.aspx Grantsmanship in Academic Emergency Medicine Kelly D. Young, MD, Harbor-UCLA Medical Center Roger J. Lewis, MD, PhD, Harbor-UCLA Medical Center

13 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Injury Surveillance Unit QISU has been analysing injury surveillance data collected by Queensland Emergency Departments since Currently 17 Queensland emergency departments participate in QISU data collection. This data allows us to develop injury profiles based on age, sex, injury mechanism, injury type, location, occupation, time of presentation, intent etc. QISU are happy to assist with any requests for data or support. QISU data could be useful in terms of: –Describing the burden of injury in a local community or demographic group –Describing the burden of injury care on a local emergency department –Describing specific injuries that are relevant to your department (e.g. ATV injuries, MBA, drowning) –Analysing mechanism of injury to inform prevention strategies for specific injuries (e.g. falls, MVA, assault) –Putting your injury profile in a broader Queensland context QISU can also assist with injury prevention networks, academic contacts and research strategies in the area of injury mechanism and prevention. Even if your department does not collect data, we may be able to provide relevant statistics or support for your research proposal. If you are interested in starting a new collection site, we are able to offer advice, training and assistance. We recognise that data collection requires commitment and effort on the part of triage nurses in increasingly busy emergency departments. Thanks to those who have contributed to this resource over the years. Contact Dr Ruth Barker, Emergency Paediatrician, Mater Childrens Hospital, Acting Director, Queensland Injury Surveillance Unit, Queensland Safe Communities Support Centre, E: W:

14 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Research Technical Guide Developing the Methodology Defining and refining your research question Searching the literature Project management and time management Writing a research proposal Sample size calculation Sources of funding Ethics, information and consent Carrying out a pilot study Bias and confounding Validity and generalisability Pragmatic versus explanatory trials versus explanatory trials

15 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Specific Methodologies Evaluating a therapy Evaluating a diagnostic test Predicting an outcome Measuring health Surveying opinions, attitudes and beliefs Systematic reviews Measuring cost-effectiveness Qualitative research College guidance on creating surveys

16 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Writing Research Proposal ing%20A%20Research%20Proposal/default.asphttp://www.collemergencymed.ac.uk/CEM/Research/Writ ing%20A%20Research%20Proposal/default.asp

17 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Clinical Research Training On-Line Web-based Clinical Research Training On-Line Course for Principal Investigators addresses one of the essential standards (training and education) approved by the National Institutes of Health (NIH) for performing clinical research in the Intramural Research Program. All NIH intramural clinical principal investigators are required to take the course and successfully complete a final exam.

18 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation How to win that grant With examples KSHOP-OPE1%2008a.ppt Janet Gross Seeking and Obtaining Private Funding for Research This is a great powerpoint presentation for obtaining funding – see slides 5 and 6 and 69www.med.emory.edu/postdoc/docs/PrivateFundingWOR KSHOP-OPE1%2008a.ppt

19 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation The QEMRF Process 1.Registration – basic information required 2.Eligibility – who can be a Principal Investigator 3.Co-investigators – building your research team and academic links 4.Asking the right question with a focus on Emergency Medicine 5.Conducting your literature review 6.Components of a full project title, short title and lay title. 7.Lay description – keeping it to 300 words and how to make it lay 8.Preparing a solid background 9.Clear aims, research question and hypotheses 10.Significance of the project 11.Milestones 12.Ethical and other approvals 13.Research plan 14.Capacity and infrastructure 15.Budget – whats allowed and whats not, how to justify your budget 16.The Administrating institution

20 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Registration -

21 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Registration – minimal info needed Short Title Long Title Principal Investigator – contact details Budget Trainee details Submitted by

22 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Eligibility FACEM FRACP PEM Public Hospital Queensland Emergency Medicine Co-Investigators can be anyone

23 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Co-investigators Collaborate from the start Find someone who is successful at getting grants, review one of their best and work together on yours Track record –Funding –Publications –Impact of the research

24 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Collaborate – before the grant is written Applied Mathematicians Epidemiologists and Statisticians Scientists Health Economists Nursing and Allied Health Emergency Services: Fire, Ambulance, Police Professionals (Legal, Psychology, Industrial Design, Engineering etc) Community and Industry

25 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation The right question Does it really bug you at work? Are you passionate about it? Refine it into a doable project Google Hayes RB. Forming research questions. Journal of Clinical Epidemiology 2006; 59: Tugwell P, McGowan J. Finding information about the burden of disease. Journal of Clinical Epidemiology 2006; 59: Haynes RB, Sackett DL, Guyatt GH, Tugwell P. Clinical epidemiology: how to do clinical practice research 3 rd Edition. Lippincott Williams and Wilkins, Philadelphia, 2006.

26 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation The right question (Guyatt 2006) You should consider: is there sufficient doubt? what is the burden of illness? do others think that there is a problem? what is the potential economic impact of resolving the question? if the question has not been definitively answered, is it the next logical step? Guyatt G. Preparing a research protocol to improve chances for success. Journal of Clinical Epidemiology 2006; 59:

27 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Literature review Search WHO International Clinical Trials Registry Platform (ICTRP) to ensure there are no similar trials are currently underway and not yet publishedhttp://apps.who.int/trialsearch/ Make friends with a good librarian Reference the Cochrane Library – even if no reviews have been done, note that you have looked. ACEM resources Members section>Clinical Trials Group>Evidence Based Medicine Resources – Tips for beginning researcherswww.acem.org.au Health Information Research Unit (Evidence-Based Health Informatics) at McMaster University website:

28 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Titles: Short and Full Full title – include the study design, eg randomised, cohort, case-control, prospective etc See Research Proposal :http://www.petech.ac.za/robert/resprop.htm – the WHO or/and WHAT is researched; –the WHERE; –the WHEN; –the HOW; –and an indication of the ENVISAGED SOLUTION or possible NEW PRODUCT. For an abbreviated view see: O'Brien K and Wright J (2002), How to write a protocol, Journal of Orthodontics, Vol. 29, No. 1, full texthttp://jorthod.maneyjournals.org/cgi/content/full/29/1/58

29 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Lay description Media releases Used in QEMRF profile and reports No more than 300 words Give it to a lay person to read Consumer Medical Information Vocabulary cabulary%20for%20CMI%20- %20An%20Explanatory%20Note.pdf, to explain medical terms cabulary%20for%20CMI%20- %20An%20Explanatory%20Note.pdf

30 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Background Have you or your team done any work in this area before Is this research building on your work? Burden of disease National Institute of Allergy and Infectious Diseases (NIH) template with examples ocol/ ocol/

31 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Aims, research question and hypotheses Resources for Behavioral Science Researchers - - The Relationship Between the Research Question, Hypotheses, Specific Aims, and Long-Term Goals of the Project The research question should contain the basic elements of the (PICOT) – participants, intervention, comparison group and outcomes and time Aims – should include action verbs – to determine, to identify, to verify, to describe, to calculate - Ref: Ahmed AM, Hints to Prepare a Research Proposal, Education, Nov al.pdf al.pdf ecture_sloan_research_hypothesis_092508_final_gray.pdfhttp://www.ferne.org/Lectures/2008_research_lecture/ppspdf/ferne_2008_research_l ecture_sloan_research_hypothesis_092508_final_gray.pdf

32 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Hypotheses Good and bad examples of hypotheses: Conducting Successful EM Resident Research: Generating Research Ideas and Hypotheses – Powerpoint slides by Edward P. Sloan, MD, MPH, FACEP, Eg: Cost: Abdominal Stab Wound Management –Bad: Observation is cheaper than laparotomy –Good: Patients observed have a similar outcome with a 50% reduction in medical costs. ppspdf/ferne_2008_research_lecture_sloan_research _hypothesis_092508_final_gray.pdf ppspdf/ferne_2008_research_lecture_sloan_research _hypothesis_092508_final_gray.pdf

33 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation The rest Significance of the project Milestones Ethical and other approvals Research plan Capacity and infrastructure Budget – whats allowed and whats not, how to justify your budget

34 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Significance of the project Why is the question worth studying? Why is it important to Emergency Medicine? What is the boarder significance – ie to other disciplines and to the broader community? Identifying how the research will align with the goals of QEMRF to advance emergency medicine in Queensland. The purpose of the Foundation is to support high quality research directed at improving the care of patients in Emergency Departments and to develop Emergency Medicine research capacity in Queensland.

35 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Milestones Estimate the time it will take for each step – break each down to the smallest point. Double it

36 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Ethics Queensland Health asp asp Mater Health Services: Research-Ethics-Committee.aspx Research-Ethics-Committee.aspx University research departments

37 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Research Plan Step-by-step guide to setting up a clinical trial – The Royal Childrens Hospital Melbourne – Clinical Epidemiology and Biostatistics Unit (CEBU) Good examples of wording and how to write - How to write a protocol Kevin O'Brien and Jean Wright, Journal of Orthodontics, Vol. 29, No. 1, 58-61, March free full text.

38 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Schematic of Study Design Rosenberg, John P. and Yates, Patsy M. ( ) Schematic representation of case study research designs. Journal of Advanced Nursing, 60 4: A simple example of a schematic can be found in Lang, Tom (2006) Documenting Research in Scientific Articles: Guidelines for Authors: Reporting Research Designs and Activities. Chest, 130; Use word – tables or drawing, PowerPoint, Visio or Mac products.

39 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Capacity and Infrastructure Demonstrate the capacity to complete the research within time and funding constraints. Document here if the team have worked together successfully previously. Cover all components required to complete the research and write it up.

40 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Resources Emergency Medicine Journal 2002;19: ; doi: /emj © 2002 BMJ Publishing Group Ltd and the College of Emergency Medicine. RESEARCH SERIESCollege of Emergency Medicine Clinical research in emergency medicine: putting it together A M T Good 1 and P Driscoll 2 1 Accident and Emergency Department, Royal Liverpool University Hospital, Liverpool, UK 2 Accident and Emergency Department, Hope Hospital, Salford, UK ABSTRACT The difficulties in conducting good clinical research in emergency medicine can be overcome. This article will begin by identifying the main difficulties faced by the emergency medicine researcher. It will then discuss some solutions through the development and application of the research protocol. Finally, recommendations will be made with regard to writing for publication.

41 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Networking Wright, D, Crouch, R, Clancy, M (2005). Role of networks in supporting emergency medicine research: findings from the Wessex emergency care research network (WECReN). Emerg. Med. J. 22: [Full Text] [Full Text]

42 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Clinical Trials – Searching Registries INTERNATIONAL CLINICAL TRIALS REGISTRY PLATFORM SEARCH PORTAL The Clinical Trials Search Portal provides access to a central database containing the trial registration data sets provided by the registries listed below. It also provides links to the full original records. –Every week: Australian New Zealand Clinical Trials Registry, ClinicalTrials.gov, ISRCTN –Every 4 weeks: Chinese Clinical Trial Register, Clinical Trials Registry - India, German Clinical Trials Register, Iranian Registry of Clinical Trials, Sri Lanka Clinical Trials Registry, The Netherlands National Trial Register

43 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Clinical Trials Register your Clinical Trial: QEMRF GCP Protocol Template: EMRF%20GCP%20Protocol%20Template%20V1%2016 %20Sep% doc EMRF%20GCP%20Protocol%20Template%20V1%2016 %20Sep% doc Queensland Clinical Trials Centre: Queensland Clinical Trials Network: Protocol Workbook - Wombat Collaboration:

44 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Clinical Trials ACEM website>Members>Clinical Trials Group>EMCTG Trial Submission – Peer review and endorsement process Predict – Paediatric Research in Emergency Departments International Collaborative Australian Clinical Trial Handbook (A simple, practical guide to the conduct of clinical trials to International standards of Good Clinical Practice (GCP) in the Australian context Trial Protocol Tool – help with writing trial protocols: The Trial Protocol Tool: the PRACTIHC software tool that supported the writing of protocols for pragmatic randomized controlled trials Journal of Clinical Epidemiology, Volume 59, Issue 11, Pages S. Treweek, K. McCormack, E. Abalos, M. Campbell, C. Ramsay, M. Zwarenstein

45 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Data Management "Clinical Data Acquisition Standards Harmonization" document from the "Clinical Data Interchange Standards Consortium" Draft guidelines for Quality Registries. The parent site hing.nsf/Content/PriorityProgram-08 hing.nsf/Content/PriorityProgram-08

46 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Budget – whats allowed and whats not, how to justify your budget Allowed: Salary for Research Assistants, Officers, Statisticians etc Consumables Travel for the purposes of research Not allowed: Principal Investigator salary – funding via fellowships may be possible if linked to a post graduate qualification Computer hardware or software – funding should be sought from other sources for these Conference attendance

47 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation The Administrating Institution Hospital –Need to find out who should sign this off – usually the CEO or COO after legal review either by hospital lawyer or Research Office University –Research Office –Sign off may take several weeks

48 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation Publication EFFECTIVE MEDICAL WRITING Michelle Biros, MS, MD, Editor-in –Chief, Academic Emergency Medicine EQUATOR Network – Enhancing the QUAlity and Transparency Of health Research network.org/.http://www.equator- network.org/ EQUATOR Network resources enable: –Better reporting –Better reviewing –Better editing

49 Queensland Emergency Medicine Research Foundation Research-driven innovation Queensland Emergency Medicine Research Foundation Research-driven innovation At any stage feel free to contact: Catrina Codd BSc, MPH Research Manager Queensland Emergency Medicine Research Foundation c/o Australian Medical Association Queensland 88 LEstrange Tce, Kelvin Grove Qld 4059 PO Box 123, Red Hill Qld 4059 T | F E | W


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