Presentation on theme: "Integrative approach for Autoimmune disorders"— Presentation transcript:
1 Integrative approach for Autoimmune disorders Amit GummanBAMS, DAc, ND, PhD, MPHMD (West Indies)Diplomate – Acupuncture, NCCAOM
2 What is Autoimmunity?Autoimmunity: Inappropriate response of the immune system against self components.Activations of self reactive clones of T or B cells, generating humoral or cell mediated response against self antigens.
3 Immune system Under reaction to external challenge = Infection Fail to recognize internal threat = CancerOver reaction to external stimulus = AllergiesOver reaction to perceived internal challenge = ADOur immune system is eaves dropping on our conversations.
4 Major health problem.NIH estimates up to 23.5 million Americans suffer from AD. (cancer 9 million, heart disease 22 million).3% of world population.Researchers have identified different AD and suspect at least 40 additional diseases of having an autoimmune basis.
5 StatisticsNIH research funding for AD in 2003 came to $591 million. Cancer funding came to $6.1 billion,heart and stroke to $2.4 billion.Top 10 leading causes of death in female children and women in all age groups up to 64 years of age.
6 Autoimmune diseaseAD refers group of illnesses that involve almost every human organ system.Nervous, gastrointestinal, endocrine systems, skin, eyes, blood, blood vessels and other connective tissues.The underlying problem is - the body's immune system becomes misdirected and attacks the very organs it was designed to protect.Enhanced immune system in women.Women have enhanced immune systems compared to men increases women's resistance to many types of infection, but also makes them more susceptible to autoimmune diseases.
7 Risk factors Genetics Environmental factors Gender Sex hormones Infection
9 Localized Autoimmune Diseases Type 1 Diabetes mellitus (pancreas islets)Hashimoto’s thyroiditis, Graves disease (thyroid)Celiac disease, Crohn's disease, Ulcerative colitis (GI)Multiple sclerosisAddison’s disease (adrenal)Primary biliary cirrhosis, Sclerosing cholangitis, Autoimmune hepatitis (liver)Temporal Arteritis / Giant Cell Arteritis (arteries of the head and neck)
10 Diagnosis History Physical examination Medical history Blood tests, including those to detect auto antibodiesBiopsyRadiological studiesIt can be hard to diagnose an autoimmune disorder, especially in its earlier stages and if multiple organs or systems are involved.
11 Treatment Anti-inflammatory drugs Corticosteroids Pain-killing medicationImmunosuppressant drugsPhysical therapyTreatment for the deficiencySurgeryHigh dose immunosuppression
13 Concept of AGNI – IGNITE A Awareness: The center of awareness in each cell. That awareness is governed by AgniG Governor: Digestion, assimilation and transformation of matter into energy. Governs the structural and functional activities of all cells and tissues.N Nutrition: of all bodily tissues; Neutralization of toxins in the tissues.I Intelligence: Cellular, molecular, quantum intelligence for selectivity and choice.Ayurveda – 40 kinds. Internal digestive fire responsible for nutritive transformation and tissue and cellular assimilation.
18 AMA VATA MANAGEMENT PRINCIPLES INTERNALLanghana – Reducing therapy, fastingDipana – Metabolic IgnitionPachana – Digest and reduce AmaLekhana – Scraping actionVirechana – PurgationNiruhana – Enemas with medicated decoctionsVedana Nashana – Pain management, physical and emotionalVata anulomana – Evacuation of Vata
19 AMA VATA MANAGEMENT PRINCIPLES EXTERNALSvedana – HerbalisedUpanahaUshna parisheka – Warm fomentationsLepa – Applications of herbal pastes.
20 ResearchImmunomodulatory activity of Semecarpus anacardium extract in mononuclear cells of normal individuals and rheumatoid arthritis patients. Singh D, Aggarwal A, Mathias A, Naik S.J Ethnopharmacol Dec 6;108(3): Epub 2006 Jun 2.Curcumin: the Indian solid gold. Aggarwal BB, Sundaram C, Malani N, Ichikawa H.Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. Adv Exp Med Biol. 2007;595:1-75.
21 Acupuncture - ADThe different immunomodulation of indirect moxibustion on normal subjects and patients with systemic lupus erythematosus.Kung YY, Chen FP, Hwang SJ.Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. Zhen Ci Yan Jiu. 1992;17(2):126-8Experimental study on the influence of acupuncture and moxibustion on interleukin-2 in patients with rheumatoid arthritisXiao J, Liu X, Sun L, Ying S, Zhang Z, Li Q, Li H, Zhang Z, Jin B, Wang S. General Hospital of PLA, Beijing. Zhen Ci Yan Jiu Apr;34(2):83-8.
22 ResearchEffect of preventive acupuncture and moxibustion at "Guanyuan" (CV 4) on the expression of HSP 70 and HSP 70 mRNA in spleen and the contents of serum IL-2, TNF-alpha in menopausal rats. Li XH, Wang HB, Xu LL, Song XL, Zheng L, He YW, Zhang LF.