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Philippe Duneton Deputy Executive Director 17 June 2013 Top HIV diagnostics for small labs in Africa.

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Presentation on theme: "Philippe Duneton Deputy Executive Director 17 June 2013 Top HIV diagnostics for small labs in Africa."— Presentation transcript:

1 Philippe Duneton Deputy Executive Director 17 June 2013 Top HIV diagnostics for small labs in Africa

2 Long term goal of the Global Health Community 2 HIV/AIDS –GOAL: Reaching 15 million people with ARVs by 2015 WHO New 2013 Guidelines –CD4: 500 cells/mm 3 from 350 –FDCs – 1 pill a day (Tenofovir based) –Patient monitoring

3 Low access to HIV treatment: Only 9 million of 25 million people in need are now on ART 1

4 Monitoring diagnostics CD4 Viral Load Early Infant Diagnostics 4 Large modern laboratories Sophisticated equipment Highly trained staff Benefit: High volume 4,500 tests a months Samples need to be transported Result returned to patient Nyumbani, Karen, Kenya Pediatric University Hospital, Lusaka, Zambia

5 The reality of low resource settings Limitation in health infrastructure –Crowded facilities –Basic laboratory facilities –Irregular power and water supply Limitation in human resources –Few doctors –Health workers with limited training carry out most consultations 5 Quality, simple to use diagnostic and medicines are needed to assure rapid effective treatment Kiboga Referral Hospital, Uganda District Hospital, Meconta, Mozambique

6 Point of care testing Small devices Easy to use outside central laboratories Rapid results Back up power supply HIV patient monitoring –CD4 –Viral Load –Early Infant Diagnosis 1er maio, Maputo Mozambique

7 Benefits to Patients 7 Phebe Hospital, Liberia Ideal for resource limited settings – both urban and rural Decreases turn-around time – results available on same day Improves patient outcomes – prompt treatment Reduces loss to follow up – no need to return for results Reduces workload of the central laboratory

8 UNITAID's new Point of Care Projects CHAI/UNICEF Medecin Sans Frontiere FEI –OPP-ERA London School of Hygiene and Tropical Medicines AIM: Increase CD4 testing to 80% and Viral load testing to 50% in low income countries Good monitoring of patients = better care and treatment 8

9 2009 2010 PointCount NOW PointCare Technologies CyFlow® CD4 miniPOC Partec Daktari CD4 Counter Visitect® CD4 Omega/Burnet MBio CD4 System BD FACSPresto BD Biosciences Zyomyx CD4 Test 2014 Disposable Instruments 2013 Pima Analyser Alere Disposable Instruments *Estimated as of March 2013 - timeline and sequence may change. CD4 Product Pipeline*

10 2013 2014 2015 2016 Alere Q Alere LYNX Viral Load Platform NWGHF LYNX HIV p24 Antigen NWGHF SAMBA VL DDU/Cambridge Liat Analyser IQuum EOSCAPE HIV Rapid RNA Assay System Wave 80 Biosciences Gene Xpert® System Cepheid Micronics Cavidi AMP *Estimated as of March 2013 - timeline and sequence may change. No market launch date set by company. SAMBA EID DDU/Cambridge Viral Load Assay with BART Lumora Gene- RADAR® Nanobiosym RT CPA HIV-1 Viral Load Ustar BioHelix ALL Truelab PCR Molbio/bigTec Viral Load and EID Product Pipeline*

11 Call for LOIs UNITAID is pleased to announce the first Call for Letters of Intent (LOI) of its new strategic period Deadline: 22 Sep 2013 http://www.unitaid.org 11


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