Presentation on theme: "Moringa Oleifera: The Miracle Tree"— Presentation transcript:
1Moringa Oleifera: The Miracle Tree Natasha Adams,Valerie Alaimo,Brian Douglas,Diane LuceDFM 655
2The Tree of Many Names Arbol de Perlas The drumstick tree The horseradish tree (isothiocyanate)Marengo, Mlonge, Maluungay,KelorSohajnaShagara al Rauwaq (“tree for purifying”)Benzolive treeThe Miracle Tree: because every part of the plant can be used medicinally.*isothiocyanate gives bitter, sulfury taste, hence the name horseradish tree
3HistoryRomans, Greeks, and Egyptians used Ben oil for perfume, skin lotion, protection from the elementsEgyptians ate leaves and used seeds to purify waterFound in the tomb of Maiherperi in the Valley of the Kings ( BC)Brought to West Indies in 1800’s; usedas smokeless lamp oil and for salads
4Traditional UsesIndia: anemia, anxiety, asthma, blood impurities, bronchitis, cholera, conjunctivitis, diarrhea, GI disorders, ear infections, diarrhea, hypertension, headache, arthritis, scurvy, TB, sore throat, psoriasis, liver disease.Malaysia and Puerto Rico: intestinal wormsPhilippines: Anemia, glandular swelling, foodGuatemala: skin infections and soresAyurvedic Medecine: thought to cure over 300 diseases. In sub-Saharan Africa, flowers and seeds are used to treat tumors and remove bacteria. Leaves are eaten fresh or dried (crushed into a powder). Medicinal uses: used to treat tumors, headaches and sores. Also used as a body cleanser and as medicine to lower high cholesterol.
5Protein PowerhouseThe flowers, leaves, seeds and pods can be eaten in curries, stews, salads or made into tea or powder.The flowers and leaves contain all of the essential amino acidsThe plant also contains antioxidants, plant esters, beneficial fatty acids and pterogospermin; a powerful antibacterial
6Phytochemicals Quercetin: found in roots and flowers Kaempherol: lowers cholesterolVitamins A,B,C,EZeatin: also found in cornCaffeoylquinic acid: also found in artichoke leaves and green propolis. Flu Fighter?Anti-inflammatory, antihistamine, hypostensive, may reduce atherosclerosis, prostate swelling, carcinogenesis
7PhytochemicalsBeta-Sitosterol: plant ester known to help reduce blood pressureHighly concentrated in leaves which can be dried and crushed into powder or eaten raw/stewed in curry, salad, soup or tea
8Seeds Ben Oil: High Oleic Acid, three types of Vit E, used for hair care, skin care andmachine lubricantAnti-microbial. Effective v. S. Aureus, Pseudomonas AeriginosusCan be toasted or eaten green like peas
9Water Treatment Women in Sudan use seedcakes to treat Nile River water Reduces turbidity 92-98%!!RNA protein inside seed flocculates gram+/- bacteria & inhibit bacterial growthAmino acids inside seed bind to metals like CdTraditional belief that alum causes GI distress and Alzheimer’s.
10Modern Uses for Moringa Got a snakebite? (Philippines)How about leprosy?(India)Suffer from hysteria?(Puerto Rico)
12Modern Uses For Moringa Backed by EvidenceCombats malnutrition for millionsBridges gap in regions of scarcityNutrient deficiencies among children/pregnant and nursing mothersIncreases lactationSupplements intake of vitamins A, B, C, E, iron, calcium and proteinIncreases intake of antioxidantsEaten as fresh leaves or as dried powderClinics dispense in rural areas of Africa,Senegal, Somalia, Kenya
13Evidence continued….Higher infant and early childhood mortality rates in developing countries, especially arid regionsMoringa helping turn the tide in rural communitiesChildren benefit mostHigher birth rates, improved health outcomesImproves learning, bone structure, vision, vitalityDecreases incidents of anemiaSources• Birman, D. (2010). Alternatives Uncovered. Traditional Plants and Medicines: Moringa. Retrieved from:• Fahey, J. W. (2005). Moringa Oleifera: A Review of the Medical Evidence for its Nutritional, Therapeutic, and Prophylactic Properties. Trees for Life Journal, 1:5
14Antisickling Properties Nigeria: 2012Extracts of seed and flowerDosage 20 mg/mlSignificant reversal of sickled erythrocytes24 million Nigerians are carriers ofSickled Cell gene2.4 million have Sickled Cell Disease
15Antidiarrheal Properties India, 2011Study involved miceEfficacy of Moringa was compared to Loperamide (Imodium)Dosage 500 mg/k had significant resultsMagnesium Sulfate induced diarrheaMoringa 90% vs 91% protectionLoperamide
16Chemopreventive Properties by Reducing Tumor Multiplicity India, 2003Moringa oleifera drumsticks (fruit)Study involved miceDosage: 125 m/k significant increase hepatic cytochrome levelsDosage 250 mg/k reduced Tumor replication to .75 per mouse vs 5.17 in control groupHypothesized that indol-3-carbanolreduces cancer incidence
17Antibacterial Properties Against Dental Plaque Bacteria Growth India, 2011Oral bacteria cause caries, periodontal disease, and serious pathogenic potentialDosage 100 – 500 mg/mlTesting in VitroSignificant Antibacterial Inhibition againstgrowth a variety of Gram-positive oralbacteria, including S. mutans, S. aureus,
18Antimicrobial & Antifungal Properties as Phytomedicine India, 2011Moringa oleifera seed and leafDosage 15 mg/ml and ul/dishIn vitro agar mediumInhibits bacterial strains: Staph a, Vibrio cholera, E coli, Proteus mirabilis, Bacillus subtilis, Fusariam solaniInhibits fungal strains: Candida albicans, Aspergillus niger, Penicillium sp, and Mucor sp.
19The ScienceUniversity of Calcutta, India: Studied the effects of Moringa leaf extract preventing early liver injury and restoring antioxidant levels in mice fed a high-fat dietResults indicated that Moringa has both preventative and curative propertiesUniversity of Ghana (2011): Studied toxicity potentials of Moringa leaf extract powder given to rats at supra-supplementation levelsFound that levels of 3,000mg/kg body weight is genotoxic and levels of <1,000mg/kg body weight are safe
20Negative Side EffectsLeaves and Stems contain B-sitosterol: can cause some side effects such as nausea, diarrhea, indigestion, or constipationFlowers contain Quercetin: has been safely used in doses of <500mg, twice/day for 12 weeks. Long-term, High-dose still needs more research. Safely used to promote breast milk productionBark and Stem can cause uterine contractions and chemicals in the root cause fertilized egg not to be able to attach to the lining of the uterine wall. Used as a permanent birth control in some areas on India
2121Century Science Supports Thousands of Years of Folklore Peer-Reviewed Research Beginning to ValidateCenturies of Ayurvedic PracticesComplementary & Alternative Medicine Health Benefits Recognized – Especially AntibioticNon-Peer Reviewed Research Would Benefit From Rigorous Scientific Evaluation & Placebo Controlled, Randomized Clinical TrialsProblem: Herbal Supplements Not Regulated
22In Conclusion:Moringa Oleifera has enormous potential as a nutriceutical and functional foodIt could help to alleviate the problems caused by food insecurity and non-potable waterMore research is necessary