2 BISCO’s Z-PRIME Plus is a single-component priming agent used to create adhesion between indirect restorative materials and all resin containing cements.
3 Z-PRIME Plus - A proprietary Formula of concentrated MDP/Carboxylate monomers has been specifically formulated to address the current weakness in competitor’s primers and create a compelling reason to replacethem immediately!
4 Bisco Products v.s. Zirconia/Silane Competitors Product Applications ComponentsZ-PRIME™ PlusBiscoZirconia, Alumina, MetalSilica-ceramicsZirconia, Alumina, Metal, Silica-ceramicsBPDM, Phosphate,EthanolSilanePhosphate, Silane*Porcelain PrimerBiscoMonobond PlusIvoclar VivadentClearfil CeramicKuraray*: Silane is not stable in the presence of acidic phosphate monomer.
5 Issue of Silane Incorporation into Zirconia Primers Silane PrimerZirconia/Silane PrimerPorcelain PrimerBiscoMonobond PlusIvoclar VivadentClearfil CeramicKurarayContain: SilaneContain: Silane & Acidic PhosphatepHSelf-Condensation of Hydrolyzed SilaneSilane MethacrylatePre-hydrolyzed SilaneDe-activation of SilaneTo maintain a good shelf-life, pH of one-bottle silane primer systems should be adjusted to 4-5.
6 Z-PRIME Plus Indications For Use BISCO’s Z-PRIME™ PLUS is intended for use as a surface treatment for the following indirect restoration substrates:Zirconia (e.g. Lava, Cerec, Implant & others)Alumina (e.g. Procera)Metal/alloy (Titanium, PFM, Non-Precious, High Noble)Composite (Direct & Indirect)Endodontic Posts (Zirconia, Metal, Fiber)Intra-oral repairs
7 Primer Effect on Bond Strength of Resin Cements to Zirconia Using the new primer had a significant effect on increasing the bond strength to zirconia of the tested cements between 86% and 160% increase.G. MILLAN, M. RAAD, M. ATTAR, and D. NATHANSON, Primer Effect on Bond Strength of Resin Cements to Zirconia, J Dent Res 89(Spec Issue A): Abstr. 1018, 2010
8 Strong Bond Strengths to Different Substrates With Z-PRIME™ Plus with no primerCement-Self CuredZirconia23 MPa4 MPaAlumina18 MPa3 MPaTitanium22 MPaNon-precious23 MPaStainless Steel24 MPaGold20 MPaComposite27 MPa
9 Unique BenefitsUnparalleled bond strengths to Zirconia, Alumina and Metal Restorations
10 High S/C & L/C BondsSBS of Z-PRIME™ Plus on Different Dental Substrates w/ Duolink™5101520253035Fiber PostCompositeGoldRex IIIOptionStainless SteelTitaniumCeramicAluminaZirconiaSBS(MPa)No PrimerZPRIME+ -S/CZPRIME+ -L/C
11 not requiring refrigeration… Bisco’s new DuoLink™ SE Kit including Z-PRIME Plus and Bis-Silane™ offers a system that provides “Confidence in Indirect Adhesion. The stability of the chemistry is demonstrated bynot requiring refrigeration…New
12 **: Silane is not stable in the present of acidic phosphate monomer. CompetitorsProduct Applications Components Shelf-lifeZ-PRIME™ PlusBiscoReleased 2009Zirconia, Alumina, MetalZirconia, AluminaZirconia, Alumina, Metal, Silica-ceramics2y/room temp.2y/r.t.*(Duolink™)2y/rom temp.2y/refrig.*(ResiCem)2y/refrig.*(Multilink)2y/refrig.*(Multilink2y/refrig2y/refrig.*(Panavia)BPDM, Phosphate,EthanolPhosphonate,Acetonet-butyl alcoholPhosphate, Silane**AZ PrimerShofuReleased 2009Metal/Zr PrimerIvoclar VivadentMonobond PlusIvoclar VivadentReleased 2009Clearfil CeramicKuraray**: Silane is not stable in the present of acidic phosphate monomer.*: Shelf-life of its corresponding cement.
13 Unique BenefitsCompatible with light-cured and dual-cured resin luting cements
16 Durable Bonding: SBS to Zirconia After AgingAged 3 days in boiling water, equiv. to 6 years at 37 °C. Cement-Light Cured.Z-PRIME™ PlusDuolink™Bisco29 MPa (Day 1)28 MPa (6 years)Clearfil CeramicPanavia F2.0Kuraray8 MPa (Day 1)3 MPa (6 years)AZ PrimerResiCemShofu21 MPa (Day 1)18 MPa (6 years)Monobond PlusMultilink AutomixIvoclar Vivadent26 MPa (Day 1)16 MPa (6 years)
17 Durable Bonding: SBS to Zirconia After AgingAged 3 days in boiling water, equiv. to 6 years at 37 °C. Cement-Self Cured.Z-PRIME™ PlusDuolink™Bisco23 MPa (Day 1)16 MPa (6 years)Clearfil CeramicPanavia F2.0Kuraray9 MPa (Day 1)2 MPa (6 years)AZ PrimerResiCemShofu13 MPa (Day 1)6 MPa (6 years)Monobond PlusMultilink AutomixIvoclar Vivadent11 MPa (Day 1)7 MPa (6 years)
18 Comparison of Zirconia Restoration Luting Options: SBS to Zirconia Cement-Self CuredResin Modified Glass Ionomer CementsRelyX Luting+(3M ESPE)FujiCEM (GC)SmartCem2(Dentsply)BisCem (Bisco)UniCem (3M ESPE)Z-Prime™ Plusw/ Duolink™ (Bisco)Duolink (Bisco)4 MPa8 MPaSelf-Adhesive Resin Cements11 MPa12 MPa6 MPaPrimer w/ Resin Cement23 MPaTraditional Resin Cement without Primer (Control)4 MPa
19 Average Shear Bond Strength of Zirconia Primers with their Corresponding Self-cure Resin Cements
20 Phosphate Monomer (MDP), BPDM, ethanol Contains:Phosphate Monomer (MDP), BPDM, ethanolStrong Bond between Resin-cements/composites and:ZirconiaAluminaMetalsTitanium, Stainless steel, Rexilium, Option, GoldCompositesInstruction for Use:Apply 1-2 coatsDryProceed with cementation.Zr, Al, orMetal etcDentinZ-PRIME PLUSDuolink
21 Technique For Placement Clean the internal surface of the restoration; rinse and air dry.Apply 1-2 coats ofZ-PRIME™ Plus, uniformly wetting the internal surface. Dry with an air syringe for 3-5 seconds.Proceed with cementation using a luting cement (e.g. DUO-LINK™).
22 Cementing Zirconia Crowns Z-PrimeDZrBisCemFor Full/Retentive Zr Crowns use Biscem® with Z-PRIME™ Plus
23 Bonding Zirconia Crowns Z-PrimeDZrAdhesiveDuoLink CementShort/Tapered, Non-retentive Zr Crown adhesively bond with Resin Cement
24 New zirconia primer improves bond strength of resin-based cements. “Improved marginal adaptation, prevention of microleakage,increased fracture strength, and increased retention insituations where mechanical retention does not exist constitute the benefits of a stable and durable resin bond tozirconia.”Magne P, et al. New zirconia primer improves bond strength of resin-based cements. Dent Mater (2009), doi: /j.dentalNew zirconia primer improves bond strength of resin-based cements.
25 New zirconia primer improves bond strength of resin-based cements. “The groups where the experimental zirconia primer (ZrP-groups) was used presented the highest mean bond strength values.”“The groups that did not receive the experimental primer (NP groups)and the group treated with the MDP-containing primer(CCP-group) presented the lowest mean bond strength values”Magne P, et al. New zirconia primer improves bond strength of resin-based cements. Dent Mater (2009), doi: /j.dental
26 “Confidence in Adhesion” Proprietary MDP and carboxylic acid monomersSignificantly enhances bond strengths of other resin cements*Compatible with light-cured and dual-cured resin luting cementConvenient, single bottle delivery offers ease of dispensingFast/Predictable Cementation*Data on file, BISCO, Inc.