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What Does BRCA Have to Do With It? PARP Inhibitors in Ovarian Cancer

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Presentation on theme: "What Does BRCA Have to Do With It? PARP Inhibitors in Ovarian Cancer"— Presentation transcript:

1 What Does BRCA Have to Do With It? PARP Inhibitors in Ovarian Cancer

2

3 Program Goals

4 Ovarian Cancer Overview

5 PARP Inhibition in Ovarian Cancer

6 Testing for BRCA1/2 Mutations

7 PARP Inhibitors Under Development

8 Olaparib in Patients With BRCA1/BRCA2 Ovarian Cancer

9 PARP Inhibitors in Patients With BRCA1/BRCA2 Ovarian Cancer

10 PARP Inhibitors as Maintenance Therapy

11 Biomarkers to Measure PARP Inhibitor Response

12 PARP Inhibitors and Chemotherapy

13 Olaparib Maintenance Therapy

14 Velaparib in Patients With Recurrent Disease

15 Major Toxicities of PARP Inhibitors

16 Outstanding Questions

17 Abbreviations

18 References

19 References (cont)

20 References (cont)

21 References (cont)


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