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Www.flowcytometryservices.co.uk. History Dr Darren Sexton (MED), Mr Geoff Carruth (REE), Dr Ailsa Harpur (REE) bid for EEDA Capital Investment for Life.

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Presentation on theme: "Www.flowcytometryservices.co.uk. History Dr Darren Sexton (MED), Mr Geoff Carruth (REE), Dr Ailsa Harpur (REE) bid for EEDA Capital Investment for Life."— Presentation transcript:

1 www.flowcytometryservices.co.uk

2 History Dr Darren Sexton (MED), Mr Geoff Carruth (REE), Dr Ailsa Harpur (REE) bid for EEDA Capital Investment for Life Sciences Competition 2008 BD Aria II Sorter purchased and housed in Biomedical Research Centre 2009 Joint Faculty of Science and Faculty of Health appointment of Dr Andrew Goldson 2009 Further investment; Accuri C6 Analyser

3 BD FACS Aria II: 70,000 events per second Sort into tubes, plates (6, 24, 48, 96, 384-wells) or onto microscope slides. 4 lasers (488nm, 633nm, 405nm, 375nm) complex multi-colour analysis; 15 parameter analysis Accuri C6 10,000 events/second 2 lasers (blue 488nm and red 640nm) 6 parameter analysis

4 Flow Cytometry facilitates cell and particulate analysis…. Particle size and granularity Fluorescent colour detection and intensity measurement Colour associated with probe of interest..... myriad probes Techniques versus applications eg Annexin V/PI staining is established Viability technique Application: Cancer drug screening, nutraceutical assessment etc

5 Bespoke flow cytometric sample analysis including: Services: Cell sorting Cell cycle analysis Apoptosis analysis Multicolour analysis Functional analysis Stem Cell analysis

6 Whats the process? Initial Enquiryquotationinvoicing Managed consultancy - UEA Consulting Ltd We can also suggest additional expertise and know-how linked to your needs. Sample Preparation? 1.You provide samples 2.We can prepare samples Dr A Goldson or KT technician Mr Matt Jefferson DesignAnalysisInterpretation

7 The Greater Environment Buying into a network of expertise: Norwich Flow Cytometry Network In conjunction with Dr Roy Bongaerts, Institute of Food Research Worldwide Flow Cytometry Network Core Facilities Managers consortia Imaging and Flow cytometry

8 Biosciences and Biotechnology Health and Life Sciences Pharmaceutical Diet and Health Industry Sectors Food and Drink Nutraceuticals Human, Animal and Plant Biotechnology Healthcare technology (eg infection control) Emerging stem cell applications Nanotechnology applications Expertise BMRC

9 Biomedical Research Centre £16.5M state-of-the-art infrastructure School of Biological Sciences and School of Medicine, Health Policy and Practice BMRCs Disease Modelling Unit Containment Level 3 laboratory for handling pathogenic organisms

10 Clinical Research and Trials Unit £3.5M state-of-the-art infrastructure Phase 1 and 2 trials 6 bedded inpatient facility with dedicated IT access, sample preparation room, kitchen and patient toilet New 9 clinic room outpatient facility with shower, kitchen, sample preparation Archive facilities

11 2500 scientists 9000 staff 30 innovative companies Research budget >£125 million p.a Norwich is ranked 4 th in the UK for the number of most highly cited scientists Norwich Research Park

12 GSK drug efficacy cell signalling redefining the role of an immune cell in disease with respect to its progenitors AKL nutraceuticals in COPD Inflammation markers in processed sputum Some Clients

13 Dr Darren W Sexton Lecturer in Immunology & LTN Business Fellow BioMedical Research Centre Faculty of Health University of East Anglia Norwich UK NR4 7TJ Tel: +44(0)1603 593321 Fax: +44(0)1603 591750 E-mail: d.sexton@uea.ac.ukd.sexton@uea.ac.uk Contact Details P LEASE DIRECT ALL BOOKINGS AND BUSINESS ENQUIRES TO D R A NDREW G OLDSON IN THE FIRST INSTANCE. Dr Andrew Goldson Flow Cytometry Services BioMedical Research Centre University of East Anglia Norwich UK NR4 7TJ Tel: +44(0)1603 591607 Fax: +44(0)1603 591750 E-mail: A.Goldson@uea.ac.ukA.Goldson@uea.ac.uk


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