Presentation on theme: "FOLLOW UP IN THALASSEMIA CLINIC"— Presentation transcript:
1FOLLOW UP IN THALASSEMIA CLINIC Presented by:Dr. Afsana Jahan (PGT)Dr. Aditi Baruah (MD); Dr. P. Bishwanath (MD)Department of PaediatricsAssam Medical College & Hospital, Dibrugarh
2IntroductionThalassemia is the commonest chronic haematological disease needing repeated blood transfusion.North-East specially Assam is a reservoir of abnormal haemoglobins & also thalassemia because of ethnic diversity of the inhabitants.Present thalassemia clinic was established in April’2005, AMCH, Dibrugarh where regular follow-up of thalassemia pateints are done.
3Aim of the StudyTo study the follow-up cases of haemo- globinopathy with special reference to thalassemia in thalassemia clinic
4Materials & Methods Place of Study : Thalassemia clinic, AMCH Period of Study : May’2005 to Oct’2007Study universe : 50 diagnosed and registered cases of HaemoglobinopathySelection criteria : Cases of Haemoglobinopathy diagnosed by HPLC.
12Effect of chelation on Serum Ferritin No. of patientsDrug and dosemg/kg/dayLength of studyS. Ferritin level (μg/L)InitialFinal16Deferiprone50 – 1001yr326114204Desferoxamine35 – 55319013923Combined9months52611276
16Problems in Thalassemia clinic Family study and convincing parents and relatives for necessity of the test.Irregular follow-up visits.Irregular blood transfusionLack of voluntary blood donation.Cost of filters and chelation therapy limits their use.Cost of different laboratory tests.
17Need of the HOUR! Public awareness. Education of health professional. Antenatal diagnosis.Emphasis on conventional treatment in particular chelation in view of its high efficacy.Cure of the disease with increasing possibility of bone marrow transplantation and gene therapy.Concrete support for achieving high standard for management of thalassemia in this part of Country.
18ConclusionThalassemia clinic is playing an important role in making thalassemia a preventable, manageable and curable disease in prospect of high incidence in this region.