Presentation on theme: "Hematology – Maureen McCullaugh Blood Gas Analysis – Mick Garrett"— Presentation transcript:
1 New Year’s Launch of Six New Technologies for Veterinary Clinical Pathology Hematology – Maureen McCullaughBlood Gas Analysis – Mick GarrettEndocrinology – Joel Eluk, Penny FurneyFlow Cytometry – Inese Berzina, Amanda Lawler, Emma O’NeillMultiplex Immunoassay – Marianna Serra, Penny FurneyCellomics – Margarida Domingos
2 Novel State-of-the-Art Biomarker Technologies at UCD UVH ImmunologyHematologyCellomicsAdviaInCellGuavaImmunochemistryBlood Gas AnalysisImmunochemistryCentaurMSDRapidLab 1200
3 Multiparameter Hematology System: ADVIA 2120 Biggest advance in hematology technology for a generation in sensitivity, specificity and parameters addedApplicable to other body fluids eg effusions, BALF, CSF, & BM. Novel parameters eg reticulocyte size, maturity & Hb (most sensitive measure of Fe status), of platelet size & activation, of neutrophil myeloperoxidase, & of extracellular versus intracellular HbManaged by Maureen McCullaugh
4 RapidLab 1200: Blood Gas Analyser latest model in market placedelivers results for all parameters in 1 minmaintenance-free, cartridge-based systemLIMS interfaceableMicrosampler – as little as 30 uLComprehensive analytic panel: blood gas (pH, pCO2, pO2); electrolytes (Na+, K+, Ca++, CI- ); Metabolic (glucose, lactate)Managed by Mick Garrett in out-of-hours / student labSample Port: Automatic sampling with a single port for syringe and capillary samples. Complete with automatic clot detection and clearance, short sample and bubble detection. Can backflush to clear so don’t have to replace cartridge.
5 Centaur CP Numerous Parameters Managed by Joel Eluk and Penny Furney automated Immunoanalyzerlatest model in market placereplaces ImmuliteNumerous ParametersThyroid T4, T3, TSHReproductive eg progesterone, estradiol, testosteroneAdrenal eg Cortisol (dog)Cardiac eg troponin, CK-MB (dog, horse)Vit B12 and folateInsulinSkeletal Muscle troponinManaged by Joel Eluk and Penny Furney
6 Guava – Personal Flow Cytometer smallest and easiest to use in marketplace2-angle scatter, 4 colorbeing developed for use for immunophenotyping of lymphoma and leukemiaAssessment of cell viabilityManaged by Inese Berzina, Amanda Lawler, and Emma O’Neill
7 MSD 2400 latest model in market place automated mulitplexing immunoanalyzerlatest model in market placefor high throughputting, needing microvolume testing (25 uL vs 150 uL), needing mutliplexingassay development possiblepanels of mulitple cytokines and chemokinescardiac panel of biomarkersreproductive hormonesManaged by Marianna Serra, Penny Furney
8 High Content Analysis & Hormesis ♦ Automated microscopy ♦ 96-well plate in incubator♦ Live-cell, image analysis ♦ Single cell, populations, well l♦ Real-time, kinetic, multiplex ♦ Intracellular location♦ Structure & function ♦ Managed by Margarida Domingos
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