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New Years Launch of Six New Technologies for Veterinary Clinical Pathology Hematology – Maureen McCullaugh Blood Gas Analysis – Mick Garrett Endocrinology.

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Presentation on theme: "New Years Launch of Six New Technologies for Veterinary Clinical Pathology Hematology – Maureen McCullaugh Blood Gas Analysis – Mick Garrett Endocrinology."— Presentation transcript:

1 New Years Launch of Six New Technologies for Veterinary Clinical Pathology Hematology – Maureen McCullaugh Blood Gas Analysis – Mick Garrett Endocrinology – Joel Eluk, Penny Furney Flow Cytometry – Inese Berzina, Amanda Lawler, Emma ONeill Multiplex Immunoassay – Marianna Serra, Penny Furney Cellomics – Margarida Domingos

2 Novel State-of-the-Art Biomarker Technologies at UCD UVH Hematology Immunology Advia Immunochemistry Centaur MSD Guava Cellomics InCell Blood Gas Analysis Immunochemistry RapidLab 1200

3 Multiparameter Hematology System: ADVIA 2120 Biggest advance in hematology technology for a generation in sensitivity, specificity and parameters added Applicable to other body fluids eg effusions, BALF, CSF, & BM. N ovel parameters eg reticulocyte size, maturity & Hb (most sensitive measure of Fe status), of platelet size & activation, of neutrophil myeloperoxidase, & of extracellular versus intracellular Hb Managed by Maureen McCullaugh

4 Sample Port: Automatic sampling with a single port for syringe and capillary samples. Complete with automatic clot detection and clearance, short sample and bubble detection. Can backflush to clear so dont have to replace cartridge. Microsampler – as little as 30 uL Comprehensive analytic panel: blood gas (pH, pCO 2, pO 2 ); electrolytes (Na +, K +, Ca ++, CI - ); Metabolic (glucose, lactate) Managed by Mick Garrett in out-of-hours / student lab RapidLab 1200: Blood Gas Analyser latest model in market place delivers results for all parameters in 1 min maintenance-free, cartridge-based system LIMS interfaceable

5 Numerous Parameters Thyroid T4, T3, TSH Reproductive eg progesterone, estradiol, testosterone Adrenal eg Cortisol (dog) Cardiac eg troponin, CK-MB (dog, horse) Vit B 12 and folate Insulin Skeletal Muscle troponin Managed by Joel Eluk and Penny Furney Centaur CP automated Immunoanalyzer latest model in market place replaces Immulite

6 Guava – Personal Flow Cytometer smallest and easiest to use in marketplace 2-angle scatter, 4 color being developed for use for immunophenotyping of lymphoma and leukemia Assessment of cell viability Managed by Inese Berzina, Amanda Lawler, and Emma ONeill

7 Managed by Marianna Serra, Penny Furney MSD 2400 automated mulitplexing immunoanalyzer latest model in market place for high throughputting, needing microvolume testing (25 uL vs 150 uL), needing mutliplexing assay development possible panels of mulitple cytokines and chemokines cardiac panel of biomarkers reproductive hormones

8 Automated microscopy 96-well plate in incubator Live-cell, image analysis Single cell, populations, well l Real-time, kinetic, multiplex Intracellular location Structure & function Managed by Margarida Domingos High Content Analysis & Hormesis


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