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Differential immune responses to acute lower respiratory illness in early life and subsequent development of persistent wheezing and asthma  Fernando.

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Presentation on theme: "Differential immune responses to acute lower respiratory illness in early life and subsequent development of persistent wheezing and asthma  Fernando."— Presentation transcript:

1 Differential immune responses to acute lower respiratory illness in early life and subsequent development of persistent wheezing and asthma  Fernando D. Martinez, MD, Debra A. Stern, MS, Anne L. Wright, PhD, Lynn M. Taussig, MD*, Marilyn Halonen, PhD  Journal of Allergy and Clinical Immunology  Volume 102, Issue 6, Pages (December 1998) DOI: /S (98) Copyright © 1998 Mosby, Inc. Terms and Conditions

2 Fig. 1 Geometric mean total serum IgE levels (IU/mL ± SEM) in acute and convalescent serum samples for persistent wheezers (n = 49), transient early wheezers (n = 88), and children who had nonwheezing LRIs (n = 42). Differences between acute and convalescent means were analyzed by paired t tests for each group. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

3 Fig. 2 Mean percent (A) and number (B) of peripheral blood eosinophils (± SEM) in acute and well-baby serum samples for persistent wheezers (n = 33), transient early wheezers (n = 66) and children who had nonwheezing LRIs (n = 43). Differences between well-baby and acute means were analyzed by paired t tests for each group. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions


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