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Marcos Burgos M.D. Medical Director Tuberculosis Program, NM DOH Department of Medicine, Veteran Affairs Medical Center, The University of New Mexico School.

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Presentation on theme: "Marcos Burgos M.D. Medical Director Tuberculosis Program, NM DOH Department of Medicine, Veteran Affairs Medical Center, The University of New Mexico School."— Presentation transcript:

1 Marcos Burgos M.D. Medical Director Tuberculosis Program, NM DOH Department of Medicine, Veteran Affairs Medical Center, The University of New Mexico School of Medicine, Albuquerque, NM. A Homeless Alcoholic Patient with TB October 23, 2012 Durango, Colorado

2 TB case November 2008 paramedics brought to the ER a 52 year old Navajo man that was found on the streets acutely intoxicated with ETOH. In the ER the patient had an alcohol level of 325 On evaluation, the patient was found to have a chest X-ray with a large left apical cavity. The patient gave a history of homelessness, history of tuberculosis treatment in the past and a current cough and weight loss of a couple of months duration

3 CXR/CT

4 TB case Multiple sputum samples were found to be 4+ for AFB and MTB complex probe positive. He was admitted to the Medical Intensive Care Unit for management of alcohol withdrawal, and he was started on 5 drugs: isoniazid, rifampin, ethambutol, pyrazinamide and moxifloxacin for presumed tuberculosis disease and superimposed pneumonia. The tuberculosis programs was notified and the patient was interviewed and records reviewed

5 What other information will you want to know? What treatment did the patient get in the past?

6 TB case - PMH The patient is homeless and an alcoholic for most of his adult life February 1992 the patient was diagnosed with pulmonary tuberculosis in Utah and was started on IRP November 1992 readmitted to McKay-Dee Hospital in Ogden, Utah Patient left against medical advice and lost again to follow up

7 TB case - PMH April 1993 readmitted in with a febrile illness, hypoxia and shortness of breath and a chest X-ray with a miliary pattern The patient again lost to follow up and because of poor compliance the patient is court ordered to receive treatment under DOT in Oct The patients tuberculosis isolate from May 5, 1993 was susceptible to all drugs

8 TB case - PMH In addition to Ogden, Utah, the patient received treatment in Boise, Idaho, and in Eugene, Oregon where he completed treatment for pulmonary TB in January 1994 There are no records of the type of treatment he received. After this episode of tuberculosis, he was evaluated in California and Colorado for active tuberculosis in 2001 and 2003.

9 TB case A sputum sample was sent to the California State Laboratory for rapid susceptibility testing (molecular beacons). Rapid susceptibility results became available on November 22 and the M. tuberculosis isolate was found to have resistant mutations for isoniazid and rifampin (MDR-TB)

10 MDR-TB case MDR-TB treatment: ethambutol 1200 po QD, pyrazinamide 1250 po QD, cycloserine 250 mg po BID, ethionamide 500 mg po BID, moxifloxacin 600 mg po QD and amikacin 1000 mg IV TIW. In addition to MDR-TB disease, the patient was found by psychiatry to be ETOH dependent with a depressive disorder. The patient refused referral to an alcohol treatment center. Susceptibility results by standard methods were still pending.

11 Can we treat this case as an outpatient?

12 MDR-TB case The patient was deemed a poor candidate for outpatient treatment Potential risk to public health History of non-adherence to treatment for TB disease History of homelessness and an alcohol abuse, both commonly associated with non-adherence. The patient remained in the hospital after he was determined to be non-infectious as the program struggled to prepare for the next phase of his treatment

13 MDR-TB case TB program has limited resources to retain high risk patients and provide a regimen for MDR TB DOH worked together with HIS to come up with the funds to pay for an inpatient facility In the past New Mexico had a similar case for which IHS and DOH split up the cost for an inpatient treatment of a MDR-TB case at the Center for Infectious Diseases (TCID) in San Antonio, Texas.

14 TB case The results of drug susceptibility testing by standard methods took more than 8 weeks to become available The drug susceptibility results showed that the isolate was susceptible to all primary and secondary drugs Due to the discrepancies in results from standard methods and the rapid method, the initial culture was sent to the California State Laboratory for molecular beacons The isolate did not have any resistant mutations

15 TB case The patient was no longer infectious He was started on isoniazid, rifampin, and pyrazinamide and the patient was discharged from the hospital to a motel room arranged and paid by the TB control program. The patient started receiving his treatment under DOT with close follow up by the TB program The patient completed additional 6 months of treatment

16 TB case The diagnosis of TB opened the door for the development of a trusting relationship with the TB program that eventually allowed him to stay sober and obtain an apartment The cost of his hospitalization: $160,000

17 Tuberculosis in an Urban Setting M. Frances Vasquez, M.S. Tuberculosis Case Manger Stanford Public Health Office Albuquerque, NM

18 Initial Situation Phone call, we have a new client at Lovelace Hospital Help him apply for General Assistance Apply for Institutional level care He may qualify for D&E Waiver

19 General History First DOT on Age: 51 History of Alcoholism and Homelessness BAC was.325 when admitted. Client was malnourished and gave a history of previous injuries and hospitalizations.

20 First Visit Met client on wearing my endearing ensemble of N-95 mask, gown and gloves I am one of 3 or 4 people in the room talking to him. He receives lots of information but speaks very little.

21 Homework GA is $266 per month Needs photo ID for Food Stamps Needs Birth Certificate – no record in NM system Ageing and Long Term Services stated wait list is over 2 years; do not think my client would qualify If found incompetent, check out guardianship. Homeless shelters may be best option for persons w/o an income. GA is $266 per month Needs photo ID for Food Stamps Needs Birth Certificate – no record in NM system Ageing and Long Term Services stated wait list is over 2 years; do not think my client would qualify If found incompetent, check out guardianship. Homeless shelters may be best option for persons w/o an income.

22 Surprise! On visit to client on , he told Dr. Burgos that he finished his TB medicine in 1994 in Eugene, OR. Stated he started treatment in Ogden, UT., then moved to Boise Idaho and then completed treatment in Oregon. Arrived in ABQ two weeks ago from Kingman AZ and before that he lived in Phoenix. BAC was.325 when admitted. On visit to client on , he told Dr. Burgos that he finished his TB medicine in 1994 in Eugene, OR. Stated he started treatment in Ogden, UT., then moved to Boise Idaho and then completed treatment in Oregon. Arrived in ABQ two weeks ago from Kingman AZ and before that he lived in Phoenix. BAC was.325 when admitted.

23 Phone call received from sister. Reported that mother had active TB in 1950s and was treated in a sanatorium in Albuquerque.

24 a Around this time client given neuropsychological evaluation. Found incompetent. Makes our job easier. Sister calls and complains that the neuropsych eval needs to be in Navajo, his native language. Navajo interpreter difficult to find. Finally I recruit our WIC clerk from Cuba to come and interpret. Client refuses to use her! Client is more cooperative and responsive during second evaluation and is found to be competent.

25 Building Rapport and Trust Inquired about ID. Client stated that he has no documents on his person or in his wallet. Began to stop in when time permitted to spend time with client and make small talk. I asked him if there was anything he was craving. Began to bring burritos from home or snacks. One day he told me he had an AZ ID and a Social Security card! Inquired about ID. Client stated that he has no documents on his person or in his wallet. Began to stop in when time permitted to spend time with client and make small talk. I asked him if there was anything he was craving. Began to bring burritos from home or snacks. One day he told me he had an AZ ID and a Social Security card!

26 I felt like...

27 Isolation Client was in isolation about 4 months. Had lots of time to think about his situation and his life. Decided to quit drinking while in hospital. Requested, and was given, double portions of food.

28 Spent his time watching TV and he seemed to enjoy the newspaper. Revealed he could only read some of the words in the newspaper. Once client was coming to office for DOT, I began to tutor him in reading.

29 Meeting with Key Stakeholders Question as to how to proceed once found competent. Meeting with hospital staff, DOH attorneys, Indian Health Service, TB Staff, MDs regarding payment for services if client was sent to Heartland in TX. Everyone had their iron in the...

30 Upon Release Was set up in hotel to complete DOT. Set up with a few utensils for cooking. When no long infectious used local services for homeless for food, bus passes, clothes, etc. Eventually received GA Eventually received Social Security Found low-income housing for client. Has been clean and sober since he was hospitalized at the end of 2008.

31 Post Treatment I became his representative payee for Social Security. He did continue to receive reading tutoring for several months. He lives independently and is still clean and sober. He lives a fairly isolated life but manages his life well.

32 Good Outcome!

33 Marcos Burgos M.D. Department of Internal Medicine, Division of Infectious Diseases, UNM SOM Medical Director TB Program, DOH NM A homeless alcoholic patient with TB Durango, Colorado


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