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Mechanisms of Pulmonary Hypertension Related to Ventricular Septal Defect in Congenital Heart Disease  Xiangbin Pan, MD, Zhe Zheng, MD, Shengshou Hu,

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Presentation on theme: "Mechanisms of Pulmonary Hypertension Related to Ventricular Septal Defect in Congenital Heart Disease  Xiangbin Pan, MD, Zhe Zheng, MD, Shengshou Hu,"— Presentation transcript:

1 Mechanisms of Pulmonary Hypertension Related to Ventricular Septal Defect in Congenital Heart Disease  Xiangbin Pan, MD, Zhe Zheng, MD, Shengshou Hu, MD, Shoujun Li, MD, Yingjie Wei, PhD, Yajuan Zhang, MD, Xiansheng Cheng, MD, Kai Ma, MD  The Annals of Thoracic Surgery  Volume 92, Issue 6, Pages (December 2011) DOI: /j.athoracsur Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Elastic fiber and hematoxylin and eosin (H & E) staining. (A) H & E, ventricular septal defect (VSD)-alone group, ×400. (B) H & E, Transposition of the great arteries (TGA) + VSD group, ×400. (C) Elastic fiber staining, VSD-alone group, ×400. (D) Elastic fiber staining, TGA + VSD group, ×400. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Matrix metalloproteinase 2 (MMP-2) and endothelial nitrous oxide synthase (eNOS) staining. (A) MMP-2, VSD-alone group, ×400. (B) MMP-2, transposition of the great arteries (TGA) + ventricular septal defect (VSD) group, ×400. (C) eNOS, VSD-alone group, ×400. (D) eNOS, TGA + VSD group, ×400. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions


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