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Suzanne Menashi, Ph. D. , Juan S. Campa, B. Sc. , Roger M

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Presentation on theme: "Suzanne Menashi, Ph. D. , Juan S. Campa, B. Sc. , Roger M"— Presentation transcript:

1 Collagen in abdominal aortic aneurysm: Typing, content, and degradation 
Suzanne Menashi, Ph.D. *, Juan S. Campa, B.Sc., Roger M. Greenhalgh, M.D., Janet T. Powell, M.D.  Journal of Vascular Surgery  Volume 6, Issue 6, Pages (December 1987) DOI: / (87) Copyright © 1987 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

2 Fig. 1 Collagen content of media of distal aorta in aneurysmal and undilated aortas. Collagen content of aortic media is given as a percentage with, for example, 50% collagen equaling 500 mg collagen/gm dry weight and 80% collagen equaling 800 mg collagen/gm dry weight. Closed circles show data from three necropsy aortas of male patients aged 67, 69, and 75 years. Open circles show data from three necropsy aneurysms of male patients aged 67, 71, and 78 years. Journal of Vascular Surgery 1987 6, DOI: ( / (87) ) Copyright © 1987 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

3 Fig. 2 Type III collagen in aortic media. Ratio of type III collagen to total collagen is shown as percentage content. Amount of type III and type I collagen was determined by densitometric recording of characteristic bands on SDS/PAGE analysis of cyanogen bromide—cleaved collagen (200 μg). Mean ages of groups were as follows: normal, 67 ± 10 years; patients with occlusive disease, 66 ± 3 years; and patients with aneurysm, 67 ± 11 years. Journal of Vascular Surgery 1987 6, DOI: ( / (87) ) Copyright © 1987 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions


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