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Reversible airway obstruction in cystic fibrosis: Common, but not associated with characteristics of asthma  Hagit Levine, Malena Cohen-Cymberknoh, Nitai.

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Presentation on theme: "Reversible airway obstruction in cystic fibrosis: Common, but not associated with characteristics of asthma  Hagit Levine, Malena Cohen-Cymberknoh, Nitai."— Presentation transcript:

1 Reversible airway obstruction in cystic fibrosis: Common, but not associated with characteristics of asthma  Hagit Levine, Malena Cohen-Cymberknoh, Nitai Klein, Moshe Hoshen, Huda Mussaffi, Patrick Stafler, Oded Breuer, Eitan Kerem, Hannah Blau  Journal of Cystic Fibrosis  Volume 15, Issue 5, Pages (September 2016) DOI: /j.jcf Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions

2 Fig. 1 Age distribution of CF patients as associated with reversible airway obstruction: a. Age distribution stratified by change in FEV1% predicted (ΔFEV1%pred) post bronchodilator showed a younger age distribution for the patients in the group with bronchodilator reversibility (p≤0.001). b. Similarly, there was a younger age distribution for patients with change in MEF25–75% % predicted (∆MEF25–75% %pred), post-bronchodilator of ≥30% (p=0.026). Journal of Cystic Fibrosis  , DOI: ( /j.jcf ) Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions

3 Fig. 2 Markers of atopy stratified by reversible airway obstruction: a. Highest recorded IgE, distribution stratified for change in FEV1% predicted (∆FEV1 %pred). There was no difference between those with or without reversible airway obstruction (p=0.08), Mann–Whittney U test. b. Highest recorded eosinophil count (cells/mcL), distribution stratified for change in FEV1 %predicted (∆FEV1 %pred). There was no difference between those with or without reversible airway obstruction (p=0.38), Mann–Whittney U test. Journal of Cystic Fibrosis  , DOI: ( /j.jcf ) Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions


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