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Yasuhiro Hamada, Masafumi Fukagawa  Kidney International 

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1 Is hepcidin the star player in iron metabolism in chronic kidney disease? 
Yasuhiro Hamada, Masafumi Fukagawa  Kidney International  Volume 75, Issue 9, Pages (May 2009) DOI: /ki Copyright © 2009 International Society of Nephrology Terms and Conditions

2 Figure 1 Roles and regulation of hepcidin in chronic kidney disease. In chronic kidney disease (CKD) patients, including dialysis patients, there are various factors that may increase or decrease serum hepcidin levels. The total effects of these factors have not yet been fully clarified. Hepcidin may not be the star player in abnormal iron metabolism in CKD as we had originally expected. Epo, erythropoietin; GFR, glomerular filtration rate; Hb, hemoglobin. (+), increase; (-), decrease; ?, unproven. Kidney International  , DOI: ( /ki ) Copyright © 2009 International Society of Nephrology Terms and Conditions


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