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Aortic Valve Replacement Improves Survival in Severe Aortic Stenosis Associated With Severe Pulmonary Hypertension  Ramdas G. Pai, MD, Padmini Varadarajan,

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Presentation on theme: "Aortic Valve Replacement Improves Survival in Severe Aortic Stenosis Associated With Severe Pulmonary Hypertension  Ramdas G. Pai, MD, Padmini Varadarajan,"— Presentation transcript:

1 Aortic Valve Replacement Improves Survival in Severe Aortic Stenosis Associated With Severe Pulmonary Hypertension  Ramdas G. Pai, MD, Padmini Varadarajan, MD, Nikhil Kapoor, MD, Ramesh C. Bansal, MD  The Annals of Thoracic Surgery  Volume 84, Issue 1, Pages (July 2007) DOI: /j.athoracsur Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Kaplan-Meier survival curves showing the association of aortic valve replacement (AVR) with better survival in patients with severe aortic stenosis associated with severe pulmonary hypertension. The Annals of Thoracic Surgery  , 80-85DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 All patients with aortic valve replacement (AVR) (n = 287). Survival curves of AVR patients with pulmonary artery systolic pressures (PASP) partitioned around 60 mm Hg. The Annals of Thoracic Surgery  , 80-85DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Graphs showing survival of patients with propensity score matching. Note the survival advantage in both strata. (A) Stratum 1. (B) Stratum 2. (AVR = aortic valve replacement.) The Annals of Thoracic Surgery  , 80-85DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Results of sensitivity analysis showing persistence of survival benefit of aortic valve replacement (AVR) with elimination of observations up to one year. (A) First 30 days eliminated. (B) First 90 days eliminated. (C) First one year eliminated. (D) First two years eliminated. The Annals of Thoracic Surgery  , 80-85DOI: ( /j.athoracsur ) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

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