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An Uncommon Cause of Membranous Glomerulonephritis

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Presentation on theme: "An Uncommon Cause of Membranous Glomerulonephritis"— Presentation transcript:

1 An Uncommon Cause of Membranous Glomerulonephritis
Anjali A. Satoskar, MD, Paul Kovach, MD, Kevin O'Reilly, MD, Tibor Nadasdy, MD, PhD  American Journal of Kidney Diseases  Volume 55, Issue 2, Pages (February 2010) DOI: /j.ajkd Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions

2 Figure 1 Hematoxylin and eosin–stained paraffin-embedded section. The glomerulus looks unremarkable (original magnification ×400). American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions

3 Figure 2 Staining pattern for immunoglobulin G (IgG) subtypes. (A) Direct immunofluorescence shows moderate granular staining for IgG1 along the glomerular capillary wall, (B) absent staining for IgG2, (C) mild granular staining for IgG3 along the glomerular capillary wall, and (D) absent staining for IgG4 (frozen section; original magnification ×400). American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions

4 Figure 3 Electron micrograph shows scattered subepithelial electron-dense immune-type deposits, irregularly distributed (arrows) (uranyl acetate lead citrate staining; original magnification ×12,000). American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions

5 Figure 4 Electron micrograph shows endothelial tubuloreticular inclusion (arrow) (uranyl acetate lead citrate staining; original magnification ×30,000). American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions


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