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N-terminal B-type natriuretic peptide levels in pediatric patients with congestive heart failure undergoing cardiac surgery  Rowan Walsh, MD, Clark Boyer,

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Presentation on theme: "N-terminal B-type natriuretic peptide levels in pediatric patients with congestive heart failure undergoing cardiac surgery  Rowan Walsh, MD, Clark Boyer,"— Presentation transcript:

1 N-terminal B-type natriuretic peptide levels in pediatric patients with congestive heart failure undergoing cardiac surgery  Rowan Walsh, MD, Clark Boyer, MD, Jared LaCorte, MD, Vincent Parnell, MD, Cristina Sison, PhD, Devyani Chowdhury, MD, Kaie Ojamaa, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 135, Issue 1, Pages (January 2008) DOI: /j.jtcvs Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Circulating N-terminal B-type natriuretic peptide (N-BNP; in picograms per milliliter) in control (CTL) healthy children and in pediatric patients before and after cardiopulmonary bypass (CPB) surgery. The box plot encompasses the 25th to 75th percentiles, the horizontal line is the median value, and the caps represent the 10th and 90th percentiles. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Preoperative and postoperative plasma N-terminal B-type natriuretic peptide (N-BNP) levels predict postoperative outcomes. Preoperative N-terminal B-type natriuretic peptide levels showed significant positive correlation with days spent in the pediatric intensive care unit (PICU; A). Peak postoperative N-terminal B-type natriuretic peptide levels showed significant correlation with PICU days (B) and with the TISS score summed from postoperative days 1 to 3 (cumulative POD1-3; C). The line represents the best-fit linear regression curve. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions


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