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Prevention and treatment of intervertebral disc degeneration with bone marrow derived stem (stromal) cells – an in vivo study in sheep  C.C. Shu, A. Dart,

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Presentation on theme: "Prevention and treatment of intervertebral disc degeneration with bone marrow derived stem (stromal) cells – an in vivo study in sheep  C.C. Shu, A. Dart,"— Presentation transcript:

1 Prevention and treatment of intervertebral disc degeneration with bone marrow derived stem (stromal) cells – an in vivo study in sheep  C.C. Shu, A. Dart, E.C. Clarke, J. Martin, C.B. Little, J. Melrose  Osteoarthritis and Cartilage  Volume 22, Pages S28-S29 (April 2014) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1 Experimental design.
Osteoarthritis and Cartilage  , S28-S29DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Figure 2 A. Representative X-ray images at IVD level L3L4 from acute long term group. B. Disc height measurements pre- and post-injection. * P < 0.05 to BS-injected discs. Osteoarthritis and Cartilage  , S28-S29DOI: ( /j.joca ) Copyright © Terms and Conditions

4 Figure 3 Selected lesion IVD catabolic enzyme gene expressions. Data presented as fold change to NOC. *P < 0.05 between PBS and MSC. Osteoarthritis and Cartilage  , S28-S29DOI: ( /j.joca ) Copyright © Terms and Conditions


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