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Complete Response Achieved 1 Year after a Single Administration of Nivolumab in a Patient with Lung Adenocarcinoma with Negative Expression of PD-L1 

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Presentation on theme: "Complete Response Achieved 1 Year after a Single Administration of Nivolumab in a Patient with Lung Adenocarcinoma with Negative Expression of PD-L1 "— Presentation transcript:

1 Complete Response Achieved 1 Year after a Single Administration of Nivolumab in a Patient with Lung Adenocarcinoma with Negative Expression of PD-L1  Takashi Iwata, MD, PhD, Aya Yamamoto, MD, Kantaro Hara, MD  Journal of Thoracic Oncology  Volume 12, Issue 12, Pages e205-e207 (December 2017) DOI: /j.jtho Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 (A) Chest computed tomography (CT) image demonstrates right apical tumor directly invading the third and the fourth cervical vertebrae, which seemed pathologically fractured already. (B) Chest CT image obtained 9 months after the single nivolumab injection shows that the apical tumor shrank and the destroyed vertebrae were replaced by fibrous and partially calcified tissue. Journal of Thoracic Oncology  , e205-e207DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 (A) Maximum intensity fludeoxyglucose F18 (FDG) positron emission tomography projection reveals high accumulation in the right apical tumor invading the third and fourth vertebrae, mediastinal and left supraclavicular lymph nodes, and multiple liver metastases. (B) Maximum intensity FDG positron emission tomography projection 11 months after the single nivolumab injection demonstrates no FDG accumulation, and otherwise, a background level in the left supraclavicular lymph node. Journal of Thoracic Oncology  , e205-e207DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

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