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Nat. Rev. Nephrol. doi: /nrneph

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Presentation on theme: "Nat. Rev. Nephrol. doi: /nrneph"— Presentation transcript:

1 Nat. Rev. Nephrol. doi:10.1038/nrneph.2016.91
Figure 5 Cross sections of kidneys from a rat model of polycystic kidney disease (cy/+ Han:SPRD) Figure 5 | Cross sections of kidneys from a rat model of polycystic kidney disease (cy/+ Han:SPRD). a,c | Control animals. b,d | Animals treated with the epidermal growth factor receptor (EGFR) inhibitor EKI-785. Administration of EKI-785 reduced the severity of cystic disease as reflected by a decrease in kidney size, reduced cyst development and less fibrosis. Reproduced with permission from © 2003 International Society of Nephrology. Published by Elsevier Inc. Torres, V. E. et al. Kidney Int. 64, 1573–1579 (2003)102. Reproduced with permission from © 2003 International Society of Nephrology. Published by Elsevier Inc. Torres, V. E. et al. Kidney Int. 64, 1573–1579 (2003)102. Harskamp, L. R. et al. (2016) The epidermal growth factor receptor pathway in chronic kidney diseases Nat. Rev. Nephrol. doi: /nrneph


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