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A Case of Heart Failure after Treatment with Anti–PD-1 Antibody Followed by Adoptive Transfer of Cytokine-Activated Killer Cells in a Recurrent Lung Cancer Patient 

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Presentation on theme: "A Case of Heart Failure after Treatment with Anti–PD-1 Antibody Followed by Adoptive Transfer of Cytokine-Activated Killer Cells in a Recurrent Lung Cancer Patient "— Presentation transcript:

1 A Case of Heart Failure after Treatment with Anti–PD-1 Antibody Followed by Adoptive Transfer of Cytokine-Activated Killer Cells in a Recurrent Lung Cancer Patient  Hideki Kimura, MD, PhD, Yuichi Tounai, MD, Kaoru Nagato, MD, PhD, Jun-ichi Morimoto, MD, PhD  Journal of Thoracic Oncology  Volume 12, Issue 8, Pages e128-e130 (August 2017) DOI: /j.jtho Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Positron emission tomography at recurrence (January 2016) showed bilateral supraclavicular, hilar, paraaortic, and abdominal lymph node metastasis. L2 bone metastasis was also detected. Journal of Thoracic Oncology  , e128-e130DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 Electrocardiogram showed complete atrioventricular block.
Journal of Thoracic Oncology  , e128-e130DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

4 Figure 3 Creatine phosphokinase and creatine kinase-myocardial b fraction increased to 7200 IU/L (on May 19, 2016) and to IU/L 5 days later (on May 24, 2016). CPK, creatine phosphokinase; PD1, programmed death 1; CK-MB, creatine kinase-myocardial b. Journal of Thoracic Oncology  , e128-e130DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

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