Presentation on theme: "Biocidal Materials for Public Health and Consumer Products (Overview) Available Through TETRAD Technologies Group, Inc. Contact:: Dr. Martin Dudziak, PhD."— Presentation transcript:
Biocidal Materials for Public Health and Consumer Products (Overview) Available Through TETRAD Technologies Group, Inc. Contact:: Dr. Martin Dudziak, PhD (804) (757) (202) cell
An Anti-Microbial Monomer/Polymer Offering Cleaner, Faster, Safer, More Comprehensive Anti-Microbial Protection Not a serious toxin and danger like Triclosan Cheaper, faster-acting than silver/copper-based compounds Non-leaching; stays within the material Extends functional life of product treated Produces self sanitizing materials Can be applied as spray, in solution, or as powder
Benefits Non- leaching, permanent antimicrobial surface Biocide has been proven to be nontoxic, to contain no carcinogens, teratogens, mutagens or reproductive toxins Active kills instantly by disrupting the cell membrane, eliminating any possibility of mutation, adaptation or resistance Broad kill range Environmentally friendly-EPA and FDA approved The technology can be used on wide range of materials. Provides both collective and individual bio-defense protection. Added cost is modest compared to benefit. Approximately 2-5 cents per square foot of coating or 5 to 50 cents per pound of plastic or resin.
Typical Applications Individual and collective protection –Clothing, Uniforms, and other Wearable Fabrics –Carbon filters –Tent Webbing and canvas materials –Painted Surfaces –Laminate and counter tops in field operations Contamination avoidance –Bulk polymer Resins/ Plastics –Resin Concentrates –Sanitation and Health Safety Equipment Medical treatment –Medical Devices –Surgical drapes and wound dressings Nano coatings –Interior surfaces/ walls floors –HVAC ducts –Filters
Action: The Poly-Quat Antimicrobial Is bound to the product controlling Microbes on contact Is substantive to the product substrate Is not consumed when challenged by microbes Mechanically destroys the cell Will not cause microbial adaptation Functions equally in a nano coating or bulk substrate treatment process Can be added into manufacturing process or applied later Can be combined with other surface protectants (e.g., water repellant, anti-static)
The Antimicrobial Agent Why did we choose this antimicrobial? 3 (trimethoxysilyl)propyl–dimethyloctadecyl ammonium chloride Unique in the scope of its kill range/broad kill Bacteria (gram positive) Staphylococcus Aureus Bacteria (gram negative) Salmonella Typhosa Yeast Algae Fungi EPA Registered Chemically active
Antimicrobial Treatment Improves Fiber Strength ASTM standard D : Tensile Strength
Antimicrobial JSLIST Fabric Sample IDLog Kill (1) JSLIST w/ 0.2% HM (2) JSLIST W/ 0.20% HM-4072 Triton X (3) 65/35 Polyester/cotton W/ 0.2% HM-4072 and 3.6% Zonyl 7040 >7.41 (3) Boiled in water 5 min7.22 (3) Laundered 6 times6.32 (4) 100 % Cotton w/ 0.2% HM-4072 and 3.6 % Zonyl (4) Boiled in water 5 min7.07 Dynamic Shake Flask Test: E. coli, one hour, sample size 2.5 X 2.5 cm
Repeated Exposure of Treated fabric to E. coli Dynamic Shake Flask Test-E. coli 2.5 cm Sample One hour contact time
Antimicrobial Activated Carbon % HM 4072% Poly-QuatLog Kill% CTC 0.1None (Control)0 (control)1.11 E6 (cfu/mL)*79.5 Dynamic Shake Flask Test: E. coli, one hour, sample size 2.5 X 2.5 cm * Colony forming units in starting broth. The control exhibits no kill.
Polymer Applications MaterialLog Kill 0.2 % active PVC6.69 HDPE6.35 Melamine/formaldehyde7.1 Polyurethane6.44 PVOH5.54 Dynamic Shake flask test, E. coli Dynamic Shake Flask Test-E. coli 2.5 cm Sample One hour contact time
Resin Coating Systems Resin System% Poly QuatLog Kill Water Acrylic Melamine/ Al Water Borne Acrylic Urethane/ Al aged 1 week5.55 Dynamic Shake Flask Test-E. coli 2.5 cm Sample One hour contact time
HM 4072 Sanitizing Nano Coating SurfaceLog Kill Aluminum 0.2 % from IPA>7.08 Aluminum 0.2 % from Water7.08 Aluminum 0.2% From Water Leached 1 Hr4.55 Aluminum 0.02 % from IPA7.08 Stainless Steel 0.2 % From Water5.90 Glass Slides 0.2 % from Water6.24 Laminate 0.2 % from Water6.31 Dynamic Shake Flask Test-E. coli 2.5 cm Sample One hour contact time
Substrate surface Si HO OH N + CH 3 CH 3 CH 3 Cl - Octadecylaminodimethyltrihydroxy-silylpropyl Ammonium Chloride Untreated Control surface Treated surface Living Bacteria Dead Bacteria