1. Volume 64, Issue 3, Pages 950-961 (September 2003)
Vitamin E prevents renal dysfunction induced by experimental chronic bile duct ligation 
M. Clara Ortiz, Melissa C. Manriquez, Karl A. Nath, Donna J. Lager, J. Carlos Romero, Luis A. Juncos 
Kidney International 
Volume 64, Issue 3, Pages (September 2003)
DOI: /j x
Copyright © 2003 International Society of Nephrology Terms and Conditions

2. Figure 1
Representative histologic sections of a chronic bile duct ligation (CBDL) and control rat liver. (A) The CBDL rat demonstrates bile ductular proliferation without significant portal fibrosis or inflammation when compared with the liver from a (B) control animal (Trichrome stain, ×100).
Kidney International  , DOI: ( /j x)
Copyright © 2003 International Society of Nephrology Terms and Conditions

3. Figure 2
Mean arterial pressure (MAP) (A) and plasma renin activity (PRA) (B) at 21days post-sham or chronic bile duct ligation (CBDL) surgery in untreated and vitamin E–treated rats. (*) P < 0.05 versus control; (†) P < 0.05 versus CBDL.
Kidney International  , DOI: ( /j x)
Copyright © 2003 International Society of Nephrology Terms and Conditions

4. Figure 3
Blood pressures in conscious, unrestrained control (left) and chronic bile duct ligation (CBDL) rats (right).*P < vs. baseline (day 2); †P < 0.05 vs. baseline (day 2).
Kidney International  , DOI: ( /j x)
Copyright © 2003 International Society of Nephrology Terms and Conditions

5. Figure 4
Renal blood flow (RBF) and glomerular filtration rate (GFR) in the four experimental groups (control, control + vitamin E, CBDL, and CBDL + vitamin E) at 21days.*P < 0.05 vs. control; †P < 0.05 vs. CBDL. CBDL is chronic bile duct ligation.
Kidney International  , DOI: ( /j x)
Copyright © 2003 International Society of Nephrology Terms and Conditions

6. Figure 5
Diuresis and natriuresis in the four experimental groups (control, control + vitamin E, CBDL, and CBDL + vitamin E) at 21days.*P < 0.05 vs. control; †P < 0.05 vs. CBDL. CBDL is chronic bile duct ligation.
Kidney International  , DOI: ( /j x)
Copyright © 2003 International Society of Nephrology Terms and Conditions

7. Figure 6
Levels of free isoprostanes and TBARS in the (A and B) systemic circulation and in (C and D) renal vein plasma at 21days. *P < 0.05 vs. control; †P < 0.05 vs. CBDL. CBDL is chronic bile duct ligation; TBARS is thiobarbituric acid reactive substances.
Kidney International  , DOI: ( /j x)
Copyright © 2003 International Society of Nephrology Terms and Conditions

8. Figure 7
Levels of endothelin (ET) in the in the (A) systemic circulation and in (B) renal vein at 21days.*P < 0.05 vs. control; †P < 0.05 vs. CBDL. CBDL is chronic bile duct ligation.
Kidney International  , DOI: ( /j x)
Copyright © 2003 International Society of Nephrology Terms and Conditions