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Chronic sinusitis in severe asthma is related to sputum eosinophilia

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Presentation on theme: "Chronic sinusitis in severe asthma is related to sputum eosinophilia"— Presentation transcript:

1 Chronic sinusitis in severe asthma is related to sputum eosinophilia
Anneke ten Brinke, MDa,d, Diana C. Grootendorst, MSca, Judith Th. Schmidt, MD, PhDb, Francisca T. de Bruïne, MD, PhDc, Mark A. van Buchem, MD, PhDc, Peter J. Sterk, MD, PhDa, Klaus F. Rabe, MD, PhDa, Elisabeth H. Bel, MD, PhDa  Journal of Allergy and Clinical Immunology  Volume 109, Issue 4, Pages (April 2002) DOI: /mai Copyright © 2002 Mosby, Inc. Terms and Conditions

2 Fig. 1 Prevalence of nasal symptoms (left) and asthma symptoms (right) in severely asthmatic patients with extensive sinus disease (filled bars) versus those without sinus disease (open bars) . Error bars represent SEM (*P < .05). Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

3 Fig. 2 Relationship between sinus CT-scan score and level of eosinophils in peripheral blood (upper panel) , eosinophils in induced sputum (middle panel) , and NO in exhaled air (lower panel) in patients with severe asthma. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

4 Fig. 3 Relationship between sinus CT-scan score and level of FRC (upper panel) and KCO (lower panel) in patients with adult-onset severe asthma. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions


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