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Continuous Flow Left Ventricular Assist Device Outcomes in Commercial Use Compared With the Prior Clinical Trial  Ranjit John, MD, Yoshifumi Naka, MD,

Published byAnna Karolien Verbeke Modified over 5 years ago

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Presentation on theme: "Continuous Flow Left Ventricular Assist Device Outcomes in Commercial Use Compared With the Prior Clinical Trial  Ranjit John, MD, Yoshifumi Naka, MD,"— Presentation transcript:

1 Continuous Flow Left Ventricular Assist Device Outcomes in Commercial Use Compared With the Prior Clinical Trial  Ranjit John, MD, Yoshifumi Naka, MD, Nicholas G. Smedira, MD, Randall Starling, MD, MPH, Ulrich Jorde, MD, Peter Eckman, MD, David J. Farrar, PhD, Francis D. Pagani, MD, PhD  The Annals of Thoracic Surgery  Volume 92, Issue 4, Pages (October 2011) DOI: /j.athoracsur Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Kaplan-Meier actuarial survival curves for the trial and posttrial patient groups in this study. At 12 months, the survival rate was 76% for the trial group and 85% for the posttrial group (p = 0.001). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 (A) Competing outcomes analysis for the clinical trial patients (n = 486). (B) Competing outcomes analysis for the posttrial patients (n = 892 patients with at least 1 year of follow-up). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Six-minute walk test results for the trial group (black bars) and posttrial group (gray bars). There were improvements during left ventricular assist device support from baseline for both groups. Data for the 12-month interval was not determined for the trial group. The percentage of patients able to complete the test is listed below the x-axis. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 (A) Kansas City Cardiomyopathy Questionnaire (KCCQ) overall summary score for the trial group. (B) EuroQoL EQ-5D visual analog scale results for the posttrial cohort. Note: The EuroQol and KCCQ reporting intervals are different. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

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