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Impact of Allele-Level HLA Mismatch on Outcomes in Recipients of Double Umbilical Cord Blood Transplantation  Claudio G. Brunstein, Effie W. Petersdorf,

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Presentation on theme: "Impact of Allele-Level HLA Mismatch on Outcomes in Recipients of Double Umbilical Cord Blood Transplantation  Claudio G. Brunstein, Effie W. Petersdorf,"— Presentation transcript:

1 Impact of Allele-Level HLA Mismatch on Outcomes in Recipients of Double Umbilical Cord Blood Transplantation  Claudio G. Brunstein, Effie W. Petersdorf, Todd E. DeFor, Harriet Noreen, David Maurer, Margaret L. MacMillan, Celalettin Ustun, Michael R. Verneris, Jeffrey S. Miller, Bruce R. Blazar, Philip B. McGlave, Daniel J. Weisdorf, John E. Wagner  Biology of Blood and Marrow Transplantation  Volume 22, Issue 3, Pages (March 2016) DOI: /j.bbmt Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 The effect of allele-level HLA matching on clinical outcomes. (A) Incidence of neutrophil recovery ≥500/μL at day +42. (B) Incidence of platelet recovery ≥20,000/μL at day +180. (C) Incidence of grades II to IV acute GVHD. (D) Incidence of NRM at 2 years. (E) Incidence of relapse at 5 years. (F) Probability of DFS at 5 years. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

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