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Figure 1 Simplified EULAR and GRAPPA

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Presentation on theme: "Figure 1 Simplified EULAR and GRAPPA"— Presentation transcript:

1 Figure 1 Simplified EULAR and GRAPPA
treatment algorithms for predominant peripheral psoriatic arthritis5,6 Figure 1 | Simplified EULAR and GRAPPA treatment algorithms for predominant peripheral psoriatic arthritis5,6. The order of drug use proposed for patients with psoriatic arthritis (PsA) and predominant peripheral joint involvement, with a step-up approach (indicated by staggered boxes) in case of inefficacy or toxicity. *Conditional recommendation in the GRAPPA) guidelines for drugs without current regulatory approval or where recommendations are based on abstract data only. bDMARD, biologic DMARD; csDMARD, conventional synthetic DMARD; EULAR, European League Against Rheumatism; GRAPPA, Group for Research and Assessment of Psoriasisand Psoriatic Arthritis; PDE4, phosphodiesterase 4. Gossec, L. et al. (2016) Management of psoriatic arthritis in 2016: a comparison of EULAR and GRAPPA recommendations Nat. Rev. Rheumatol. doi: /nrrheum

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Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
Psoriatic Arthritis.

Psoriatic Arthritis.
Immunohistochemical (IHC) staining for CD68/CD21 and CD3/CD20 on synovial tissue (ST) of patients with inflammatory bowel disease (IBD) with onset of peripheral.

Immunohistochemical (IHC) staining for CD68/CD21 and CD3/CD20 on synovial tissue (ST) of patients with inflammatory bowel disease (IBD) with onset of peripheral.
Objective Target population: patients with psoriatic arthritis (PsA)

Objective Target population: patients with psoriatic arthritis (PsA)
Summary of TB cases across indications and trial periods

Summary of TB cases across indications and trial periods
Algorithm based on the 2016 European League Against Rheumatism (EULAR) recommendations on rheumatoid arthritis (RA) management. Algorithm based on the.

Algorithm based on the 2016 European League Against Rheumatism (EULAR) recommendations on rheumatoid arthritis (RA) management. Algorithm based on the.
Figure 1 Rheumatoid arthritis development over time in relation to the level of inflammation Figure 1 | Rheumatoid arthritis development over time in relation.

Figure 1 Rheumatoid arthritis development over time in relation to the level of inflammation Figure 1 | Rheumatoid arthritis development over time in relation.
Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 Enthesitis versus synovitis

Figure 1 Enthesitis versus synovitis
Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 Induction of immune tolerance

Figure 1 Induction of immune tolerance
Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio
Nat. Rev. Clin. Oncol. doi: /nrclinonc

Nat. Rev. Clin. Oncol. doi: /nrclinonc
Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 Metabolic profiling as a tool for studying rheumatic diseases

Figure 1 Metabolic profiling as a tool for studying rheumatic diseases
Figure 2 Therapeutic targeting of the PI3K/AKT/mTOR pathway

Figure 2 Therapeutic targeting of the PI3K/AKT/mTOR pathway
Figure 3 Simplified EULAR and GRAPPA

Figure 3 Simplified EULAR and GRAPPA
Figure 2 Simplified EULAR and GRAPPA

Figure 2 Simplified EULAR and GRAPPA
Figure 3 Transcriptome studies performed in the target

Figure 3 Transcriptome studies performed in the target

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