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Leukocyte activation in patients with venous insufficiency
Shinya Takase, MD, PhD, Geert Schmid-Schönbein, PhD, John J. Bergan, MD, FACS Journal of Vascular Surgery Volume 30, Issue 1, Pages (July 1999) DOI: /S (99) Copyright © 1999 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions
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Fig 1 Micrographs of polymorphonuclear granulocytes showing tetrazolium crystal formation after nitroblue tetrazolium reduction (A,B,C) and projection of pseudopods (D,E,F). Control blood of individuals without symptoms (A,D), patient whole blood (B, E), and naive granulocytes incubated in patient plasma (C, F). Bar represents 10 mm. Magnification is same for all panels. Journal of Vascular Surgery , DOI: ( /S (99) ) Copyright © 1999 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions
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Fig 2 Levels of nitroblue tetrazolium (NBT) reduction. NG, Naive granulocytes; Cp, control plasma; PG, patient granulocytes; Pp, patient plasma. **P < .001 and †P < .0001, compared with naive granulocytes in patient plasma. Journal of Vascular Surgery , DOI: ( /S (99) ) Copyright © 1999 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions
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Fig 3 Levels of granulocyte pseudopod formation.
NG, Naive granulocytes; Cp, control plasma; PG, patient granulocytes; Pp, patient plasma. *P < .05 and †P < .0001, compared with naive granulocytes in patient plasma. Journal of Vascular Surgery , DOI: ( /S (99) ) Copyright © 1999 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions
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Fig 4 Comparison of nitroblue tetrazolium (NBT) reduction. Patient samples were grouped into CEAP classes 2 and 3 and classes 4, 5, and 6. NG, Naive granulocytes; Cp, control plasma; PG, patient granulocytes; Pp, patient plasma. *P < .05. **P < .001. Journal of Vascular Surgery , DOI: ( /S (99) ) Copyright © 1999 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions
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Fig 5 Comparison of granulocyte pseudopod formation. Patient samples were grouped into CEAP classes 2 and 3 and classes 4, 5, and 6. NG, Naive granulocytes; Cp, control plasma; PG, patient granulocytes; Pp, patient plasma. *P < .05. **P < .001. Journal of Vascular Surgery , DOI: ( /S (99) ) Copyright © 1999 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions
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Fig 6 Hydrogen peroxide production levels in patients with chronic venous insufficiency and in asymptomatic controls. Journal of Vascular Surgery , DOI: ( /S (99) ) Copyright © 1999 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions
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