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Intestinal permeability is increased in patients with intermittent claudication  Hirohide Iwata, MD, Masahiro Matsushita, MD, Naomichi Nishikimi, MD, Tsunehisa.

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Presentation on theme: "Intestinal permeability is increased in patients with intermittent claudication  Hirohide Iwata, MD, Masahiro Matsushita, MD, Naomichi Nishikimi, MD, Tsunehisa."— Presentation transcript:

1 Intestinal permeability is increased in patients with intermittent claudication 
Hirohide Iwata, MD, Masahiro Matsushita, MD, Naomichi Nishikimi, MD, Tsunehisa Sakurai, MD, Yuji Nimura, MD  Journal of Vascular Surgery  Volume 31, Issue 5, Pages (May 2000) DOI: /mva Copyright © 2000 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 The lactulose/mannitol ratio (L/M ratio) at rest and after exercise. In control subjects, there was no significant difference between the mean L/M ratio after exercise and at rest (0.016 ± vs ± 0.008, P >.05). In patients, the mean L/M ratio after exercise was significantly higher than the mean L/M ratio at rest (0.068 ± vs ± 0.009, P <.05). The value was more than in eight of the 11 patients (72.7%). Journal of Vascular Surgery  , DOI: ( /mva ) Copyright © 2000 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 The lactulose/mannitol ratio (L/M ratio) after exercise in patients with intermittent claudication. The mean L/M ratio after exercise decreased from ± to ± after arterial reconstruction (P <.05). In 10 of 11 cases (91.0%), the ratio was within the normal limit after vascular reconstruction. Journal of Vascular Surgery  , DOI: ( /mva ) Copyright © 2000 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

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