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Outcomes of Allogeneic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: A Systematic Review and Meta-analysis  Armin Rashidi,

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Presentation on theme: "Outcomes of Allogeneic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: A Systematic Review and Meta-analysis  Armin Rashidi,"— Presentation transcript:

1 Outcomes of Allogeneic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: A Systematic Review and Meta-analysis  Armin Rashidi, Maryam Ebadi, Graham A. Colditz, John F. DiPersio  Biology of Blood and Marrow Transplantation  Volume 22, Issue 4, Pages (April 2016) DOI: /j.bbmt Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Flow diagram of the studies in meta-analysis. A total of 14 reports were studied in detail. One study was counted twice because it reported patients in first and second complete remission separately [18]. Only 1 study used myeloablative conditioning and was not analyzed [12]. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Relapse-free survival (RFS) at 6 months, 1 year, 2 years, and 3 years. Effect size (ES) is odds ratio or relative risk depending on the study. P = . is produced by the software when I2 is zero. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Overall survival (OS) at 6 months, 1 year, 2 years, and 3 years. Effect size (ES) is odds ratio or relative risk depending on the study. P = . is produced by the software when I2 is zero. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Reconstructed Kaplan-Meyer curves for relapse-free survival (RFS), overall survival (OS), cumulative incidence of relapse (CIR), and nonrelapse mortality (NRM). Pooled estimates demonstrate that allogeneic stem cell transplantation is a viable treatment option for elderly patients with acute myeloid leukemia. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

6 Figure S1 P = . is produced by the software when I2 is zero.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

7 Figure S2 Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

8 Figure S3 Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

9 Figure S4 Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

10 Figure S5 Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

11 Figure S6 Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

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