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S. Seah, D. Wheaton, L. Li, J. P. Dyke, C. Talmo, W. F. Harvey, D. J

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Presentation on theme: "S. Seah, D. Wheaton, L. Li, J. P. Dyke, C. Talmo, W. F. Harvey, D. J"— Presentation transcript:

1 The relationship of tibial bone perfusion to pain in knee osteoarthritis 
S. Seah, D. Wheaton, L. Li, J.P. Dyke, C. Talmo, W.F. Harvey, D.J. Hunter  Osteoarthritis and Cartilage  Volume 20, Issue 12, Pages (December 2012) DOI: /j.joca Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Chart of BML Kel with BML grade. Kel decreases with increasing BML size showing delayed outflow postulated to represent venous obstruction. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Representative images of DCE MRI acquisition. Notice that there is more rapid washout or clearance of the Gd compared to muscle in the lower grade 1 BML's. This implies more normal elimination and proper venous outflow. Our findings indicated that the larger BMLs (see grade 3 lesion) had a more negative Kel (more delayed clearance) indicating more delayed venous outflow. Arrow indicates location of BML. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 Relationship between pain at night while sleeping and BML grade. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions


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