Presentation is loading. Please wait.

Presentation is loading. Please wait.

Prognostic Factors of Chronic Graft-versus-Host Disease Following Allogeneic Peripheral Blood Stem Cell Transplantation: The National Institutes Health.

Similar presentations


Presentation on theme: "Prognostic Factors of Chronic Graft-versus-Host Disease Following Allogeneic Peripheral Blood Stem Cell Transplantation: The National Institutes Health."— Presentation transcript:

1 Prognostic Factors of Chronic Graft-versus-Host Disease Following Allogeneic Peripheral Blood Stem Cell Transplantation: The National Institutes Health Scale Plus the Type of Onset Can Predict Survival Rates and the Duration of Immunosuppressive Therapy  José A. Pérez-Simón, Cristina Encinas, Fernando Silva, Maria José Arcos, María Díez-Campelo, Fermín M. Sánchez-Guijo, Enrique Colado, Jesús Martín, Lourdes Vazquez, Consuelo del Cañizo, Dolores Caballero, Jesús San Miguel  Biology of Blood and Marrow Transplantation  Volume 14, Issue 10, Pages (October 2008) DOI: /j.bbmt Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Cumulative incidence of cGVHD according to standard criteria (A) and to NIH-based criteria (B). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Relapse of cGVHD in patients who responded to first-line treatment (A) and according to the NIH scale (B). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Probability of being off immunosuppression at last follow-up.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 OS and EFS for the whole series of patients (A); OS in patients with de novo, quiescent, or progressive-onset cGVHD (B); and OS in patients with mild, moderate, or severe cGVHD (C). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

6 Figure 5 OS in patients with cGVHD according to NIH score plus type of onset. OS, depending on grade of severity according to the NIH scoring system plus type of onset, was 82% for patients with mild cGVHD regardless of the type of onset and patients with moderate cGVHD with de novo onset, 70% for patients with moderate cGVHD and quiescent or progressive onset, 50% for patients with severe cGVHD and de novo onset, and 25% for patients with severe cGVHD and quiescent or progressive onset. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions


Download ppt "Prognostic Factors of Chronic Graft-versus-Host Disease Following Allogeneic Peripheral Blood Stem Cell Transplantation: The National Institutes Health."

Similar presentations


Ads by Google