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The IASLC Lung Cancer Staging Project: Proposals for the Revision of the TNM Stage Groupings in the Forthcoming (Seventh) Edition of the TNM Classification.

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Presentation on theme: "The IASLC Lung Cancer Staging Project: Proposals for the Revision of the TNM Stage Groupings in the Forthcoming (Seventh) Edition of the TNM Classification."— Presentation transcript:

1 The IASLC Lung Cancer Staging Project: Proposals for the Revision of the TNM Stage Groupings in the Forthcoming (Seventh) Edition of the TNM Classification of Malignant Tumours  Peter Goldstraw, FRCS, John Crowley, PhD, Kari Chansky, MS, Dorothy J. Giroux, MSc, Patti A. Groome, PhD, Ramon Rami-Porta, MD, Pieter E. Postmus, PhD, Valerie Rusch, MD, Leslie Sobin, MD  Journal of Thoracic Oncology  Volume 2, Issue 8, Pages (August 2007) DOI: /JTO.0b013e31812f3c1a Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Recursive partitioning and amalgamation–generated survival tree based on best stage for 17,726 cases. T and M stages (from proposed new T and M) are combined as 0/1 indicators. N stage is ordered. The number below each terminal node is the log hazard ratio, with the T1aN0M0 category as baseline. Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e31812f3c1a) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Overall survival, expressed as median survival time (MST) and 5-year survival, by clinical stage using the sixth edition of TNM (A) and proposed International Association of the Study of Lung Cancer recommendations (B). Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e31812f3c1a) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Overall survival, expressed as median survival time (MST) and 5-year survival, by pathologic stage using sixth edition of TNM (A) and proposed International Association of the Study of Lung Cancer recommendations (B). Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e31812f3c1a) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions


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