Presentation is loading. Please wait.

Presentation is loading. Please wait.

Tribological and material properties for cartilage of and throughout the bovine stifle: support for the altered joint kinematics hypothesis of osteoarthritis 

Published byJean-Marie Mercier Modified over 5 years ago

Similar presentations

Presentation on theme: "Tribological and material properties for cartilage of and throughout the bovine stifle: support for the altered joint kinematics hypothesis of osteoarthritis "— Presentation transcript:

1 Tribological and material properties for cartilage of and throughout the bovine stifle: support for the altered joint kinematics hypothesis of osteoarthritis  A.C. Moore, D.L. Burris  Osteoarthritis and Cartilage  Volume 23, Issue 1, Pages (January 2015) DOI: /j.joca Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Definitions of sample sites within the bovine stifle and the regions classified for purposes of comparison. Left: the frontal plane view of a bovine stifle joint. Center: the sagittal plane view for three flexion angles in which different samples experience cartilage–cartilage contact. Right: sampling locations on the femoral condyles and tibial plateau. The comparisons of interest are the femoral condyles vs tibial plateau, medial vs lateral, and outer femoral condyles (O) vs central femoral condyles (C) vs inner femoral condyles (I) vs shielded tibial plateau (S) vs uncovered tibial plateau (U). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Illustration of the custom microtribometer used to measure the material and functional properties of bovine articular cartilage. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 Representative data to illustrate the characterization of material properties. Left: force verses displacement curves for nominal speeds of 50, 0.5, 5, 20, and 10 μm/s, in that randomized order for a representative high functioning sample. Following the last indent the stage is held fixed until equilibrium is reached. The equilibrium contact modulus is obtained directly from that point and the dotted line represents the predicted Hertzian relationship between force and deformation. Right: the fluid load fraction is calculated for representative high and low functioning samples as a function of the prescribed indentation rate. The dark labels correspond to the force-displacement data on the left. The fits to the biphasic model from Moore and Burris16 are shown in red and were used to determine tissue permeability and tensile modulus. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

5 Fig. 4 Correlations between the functional performance and material properties for bovine articular cartilage. The functional properties of interest are the effective friction coefficient (Left), effective contact modulus (Center) and fluid load fraction (Right). The Top row contains the best overall correlation for each functional metric. The Bottom row contains the best overall correlation for each functional metric against Ec0, k, and Ec0·k. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

6 Fig. 5 Comparisons of the tribological and material properties for the femoral condyles and tibial plateaus of the bovine stifle joint. Error bars represent 95% confidence intervals. Significant differences are indicated by dissimilar letters, P < 0.05. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

7 Fig. 6 Comparisons of the tribological and material properties for the femoral central (C), outer (O), inner (I), and tibial shielded (S) and uncovered (U) regions of the bovine stifle joint. Error bars represent 95% confidence intervals. Significant differences are indicated by dissimilar letters, P < 0.05. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Download ppt "Tribological and material properties for cartilage of and throughout the bovine stifle: support for the altered joint kinematics hypothesis of osteoarthritis "

Similar presentations

Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative 

Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative 
Biomechanical, biochemical and structural correlations in immature and mature rabbit articular cartilage  P. Julkunen, T. Harjula, J. Iivarinen, J. Marjanen,

Biomechanical, biochemical and structural correlations in immature and mature rabbit articular cartilage  P. Julkunen, T. Harjula, J. Iivarinen, J. Marjanen,
Where does meniscal damage progress most rapidly

Where does meniscal damage progress most rapidly
Novel optical imaging technique to determine the 3-D orientation of collagen fibers in cartilage: variable-incidence angle polarization-sensitive optical.

Novel optical imaging technique to determine the 3-D orientation of collagen fibers in cartilage: variable-incidence angle polarization-sensitive optical.
The contribution of collagen fibers to the mechanical compressive properties of the temporomandibular joint disc  S. Fazaeli, S. Ghazanfari, V. Everts,

The contribution of collagen fibers to the mechanical compressive properties of the temporomandibular joint disc  S. Fazaeli, S. Ghazanfari, V. Everts,
The short-term effects of running on the deformation of knee articular cartilage and its relationship to biomechanical loads at the knee  M. Boocock,

The short-term effects of running on the deformation of knee articular cartilage and its relationship to biomechanical loads at the knee  M. Boocock,
Subchondral plate porosity colocalizes with the point of mechanical load during ambulation in a rat knee model of post-traumatic osteoarthritis  H. Iijima,

Subchondral plate porosity colocalizes with the point of mechanical load during ambulation in a rat knee model of post-traumatic osteoarthritis  H. Iijima,
Knee osteoarthritis patients with severe nocturnal pain have altered proximal tibial subchondral bone mineral density  W.D. Burnett, S.A. Kontulainen,

Knee osteoarthritis patients with severe nocturnal pain have altered proximal tibial subchondral bone mineral density  W.D. Burnett, S.A. Kontulainen,
Considerations in measuring cartilage thickness using MRI: factors influencing reproducibility and accuracy  S. Koo, M.S., G.E. Gold, M.D., T.P. Andriacchi,

Considerations in measuring cartilage thickness using MRI: factors influencing reproducibility and accuracy  S. Koo, M.S., G.E. Gold, M.D., T.P. Andriacchi,
J.H. Koolstra  Osteoarthritis and Cartilage 

J.H. Koolstra  Osteoarthritis and Cartilage 
Contrast-enhanced CT facilitates rapid, non-destructive assessment of cartilage and bone properties of the human metacarpal  B.A. Lakin, D.J. Ellis, J.S.

Contrast-enhanced CT facilitates rapid, non-destructive assessment of cartilage and bone properties of the human metacarpal  B.A. Lakin, D.J. Ellis, J.S.
An in vivo cross-linkable hyaluronan gel with inherent anti-inflammatory properties reduces OA cartilage destruction in female mice subjected to cruciate.

An in vivo cross-linkable hyaluronan gel with inherent anti-inflammatory properties reduces OA cartilage destruction in female mice subjected to cruciate.
Initial application of EPIC-μCT to assess mouse articular cartilage morphology and composition: effects of aging and treadmill running  N. Kotwal, J.

Initial application of EPIC-μCT to assess mouse articular cartilage morphology and composition: effects of aging and treadmill running  N. Kotwal, J.
Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis  H. Mitsuyama, M.D., Ph.D., R.M. Healey, B.S.,

Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis  H. Mitsuyama, M.D., Ph.D., R.M. Healey, B.S.,
Intraoperative validation of quantitative T2 mapping in patients with articular cartilage lesions of the knee  S.T. Soellner, A. Goldmann, D. Muelheims,

Intraoperative validation of quantitative T2 mapping in patients with articular cartilage lesions of the knee  S.T. Soellner, A. Goldmann, D. Muelheims,
Subchondral plate porosity colocalizes with the point of mechanical load during ambulation in a rat knee model of post-traumatic osteoarthritis  H. Iijima,

Subchondral plate porosity colocalizes with the point of mechanical load during ambulation in a rat knee model of post-traumatic osteoarthritis  H. Iijima,
Patient-specific chondrolabral contact mechanics in patients with acetabular dysplasia following treatment with peri-acetabular osteotomy  C.L. Abraham,

Patient-specific chondrolabral contact mechanics in patients with acetabular dysplasia following treatment with peri-acetabular osteotomy  C.L. Abraham,
Arthroscopic estimation of the extent of chondropathy

Arthroscopic estimation of the extent of chondropathy
A.C. Moore, D.L. Burris  Osteoarthritis and Cartilage 

A.C. Moore, D.L. Burris  Osteoarthritis and Cartilage 
Investigation of the frictional response of osteoarthritic human tibiofemoral joints and the potential beneficial tribological effect of healthy synovial.

Investigation of the frictional response of osteoarthritic human tibiofemoral joints and the potential beneficial tribological effect of healthy synovial.

Similar presentations

Ads by Google