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Metastatic Ocular Melanoma Presenting as a Heart-Compressing Mediastinal Mass  Michael Kiparakis, MD, George Lazopoulos, MD, PhD, Anastasios Koutsopoulos,

Published byCristina Córdoba Ramos Modified over 5 years ago

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Presentation on theme: "Metastatic Ocular Melanoma Presenting as a Heart-Compressing Mediastinal Mass  Michael Kiparakis, MD, George Lazopoulos, MD, PhD, Anastasios Koutsopoulos,"— Presentation transcript:

1 Metastatic Ocular Melanoma Presenting as a Heart-Compressing Mediastinal Mass 
Michael Kiparakis, MD, George Lazopoulos, MD, PhD, Anastasios Koutsopoulos, MD, PhD, Aikaterini Gavalaki, MD, Emmanouil Kampitakis, MD, George Chalkiadakis, MD, PhD  The Annals of Thoracic Surgery  Volume 100, Issue 4, Pages (October 2015) DOI: /j.athoracsur Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 (A) Transthoracic echocardiogram (apical four-chamber view) demonstrating an extracardiac mass (star) almost completely compressing the left atrial cavity. LV = left ventricle. (B) Computed tomographic scan of the thorax revealing a large, 8.5 × 6.8 × 6.8 cm sized, round lesion (star) in the middle and posterior mediastinum at the level of the left atrium. Compression of the left atrium is obvious. LV = left ventricle. (C) Right extended anterolateral thoracotomy revealed the large, round, solid, posterior mediastinal mass (star). (LA = left atrium; V = vertebrae.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 (A) Macroscopic view of the specimen showing a well-demarcated tumor. (B) The cut surface reveals a lobulated dark mass with sites of hemorrhage and necrosis. (C) Microscopic examination (×50) showing the morphologic characteristics consistent with malignant melanoma with melanin production. (D) Diagnosis confirmed by the positivity of several immunohistochemical markers such as Vimentin, HMB-45, S-100 protein (not shown), and Melan A (×200). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

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