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Fixed drug eruption caused by dimenhydrinate

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Presentation on theme: "Fixed drug eruption caused by dimenhydrinate"— Presentation transcript:

1 Fixed drug eruption caused by dimenhydrinate
Sophia Giatrakou, MD, Evangelia Papadavid, MD, PhD, Dimitrios Kalogeromitros, MD, PhD, Konstandinos Theodoropoulos, MD, Eugenia Toumbis-Ioannou, MD, PhD, Michalis Makris, MD, PhD, Nikolaos G. Stavrianeas, MD, PhD  Journal of the American Academy of Dermatology  Volume 64, Issue 3, Pages (March 2011) DOI: /j.jaad Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Skin lesions of patient after oral provocation test. Diagnosis of fixed drug eruption from dimenhydrinate was confirmed. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Lesion resolved in approximately 20 days with application of topical steroid cream, and had not recurred at time of our writing. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 CD8– T cells in skin lesions became reactivated after re-exposure to causative drug, documented with immunostaining using anti-CD8. (Hematoxylin counter stain; original magnification: ×40.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions


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