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There's No Place Like Home for a Neural Stem Cell

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Presentation on theme: "There's No Place Like Home for a Neural Stem Cell"— Presentation transcript:

1 There's No Place Like Home for a Neural Stem Cell
Julie A. Siegenthaler, Samuel J. Pleasure  Cell Stem Cell  Volume 7, Issue 2, Pages (August 2010) DOI: /j.stem Copyright © 2010 Elsevier Inc. Terms and Conditions

2 Figure 1 Schematic Diagram of the SVZ Stem Cell Niche
Quiescent B cells (Bq) are in a subependymal position with an apical process in contact with the ventricular space. Once activated (Ba), these cells generate transiently amplifying C cells positioned in close proximity to blood vessels. Both the ependyma and vessels express SDF1 that drives the expression of receptors that regulate proliferative behavior (EGFR) and cell adhesion (α6β1). C cells generate A cells, which then migrate to the olfactory bulb via the rostral migratory stream. Cell Stem Cell 2010 7, DOI: ( /j.stem ) Copyright © 2010 Elsevier Inc. Terms and Conditions


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