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Anti–VLA-4 antibody reduces intimal hyperplasia in the endarterectomized carotid artery in nonhuman primates  Alan B. Lumsden, MB, ChB, Changyi Chen,

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Presentation on theme: "Anti–VLA-4 antibody reduces intimal hyperplasia in the endarterectomized carotid artery in nonhuman primates  Alan B. Lumsden, MB, ChB, Changyi Chen,"— Presentation transcript:

1 Anti–VLA-4 antibody reduces intimal hyperplasia in the endarterectomized carotid artery in nonhuman primates  Alan B. Lumsden, MB, ChB, Changyi Chen, MD, PhD, John D. Hughes, MD, Andrew B. Kelly, DVM, Stephen R. Hanson, PhD, Laurence A. Harker, MD  Journal of Vascular Surgery  Volume 26, Issue 1, Pages (July 1997) DOI: /S (97) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 Histologic cross-sections at sites of carotid artery endarterectomy. Greater intimal hyperplasia developed in the control arteries (A) than in the arteries treated with anti–VLA-4 monoclonal antibody (B). L, Lumen; I, intima; M, media; A, adventitia. Blue represents collagen staining; black represents elastin staining; pink represents all other components. (Verhoeff-Masson's stain; original magnification ×100.) Journal of Vascular Surgery  , 87-93DOI: ( /S (97) ) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 1 Histologic cross-sections at sites of carotid artery endarterectomy. Greater intimal hyperplasia developed in the control arteries (A) than in the arteries treated with anti–VLA-4 monoclonal antibody (B). L, Lumen; I, intima; M, media; A, adventitia. Blue represents collagen staining; black represents elastin staining; pink represents all other components. (Verhoeff-Masson's stain; original magnification ×100.) Journal of Vascular Surgery  , 87-93DOI: ( /S (97) ) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

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