1. Drug hypersensitivity: Pharmacogenetics and clinical syndromes
Elizabeth J. Phillips, MD, Wen-Hung Chung, MD, PhD, Maja Mockenhaupt, MD, PhD, Jean-Claude Roujeau, MD, Simon A. Mallal, MBBS 
Journal of Allergy and Clinical Immunology 
Volume 127, Issue 3, Pages S60-S66 (March 2011)
DOI: /j.jaci
Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
Translational roadmap from discovery of HLA-B∗5701 association with abacavir hypersensitivity to widespread clinical implementation.
Journal of Allergy and Clinical Immunology  , S60-S66DOI: ( /j.jaci )
Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig 2
Number needed to test (NNT) to prevent 1 case of specific drug reaction. Numbers shown are for abacavir hypersensitivity, allopurinol-associated SJS/TEN/drug hypersensitivity, CBZ-associated SJS/TEN, and flucloxacillin-associated drug-induced liver disease.
Adapted from Phillips and Mallal.24
Journal of Allergy and Clinical Immunology  , S60-S66DOI: ( /j.jaci )
Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions