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Volume 4, Issue 2, Pages 123-125 (March 2018)
Acute generalized exanthematous pustulosis simulating Stevens-Johnson syndrome/toxic epidermal necrolysis associated with the use of vismodegib Oscar M. Moreno-Arrones, MD, Rosario Carrillo-Gijon, MD, PhD, Elena Sendagorta, MD, PhD, Luis Rios-Buceta, MD, PhD JAAD Case Reports Volume 4, Issue 2, Pages (March 2018) DOI: /j.jdcr Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions
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Fig 1 Clinical photograph. A and B, Confluent erythematous and edematous plaques with purpuric center affecting predominantly the trunk with a positive Nikolsky sign. Subtle pustules can be seen (A). JAAD Case Reports 2018 4, DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions
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Fig 2 Histologic picture. A, Low power view of a very large, confluent, subcorneal pustule. Collections of neutrophils are present in the dermis. B, Under a large pustule with blisterlike features and massive spongiosis, the dermis shows sparse mixed infiltrate without eosinophils. JAAD Case Reports 2018 4, DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions
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