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IV Busulfan Dose Individualization in Children undergoing Hematopoietic Stem Cell Transplant: Limited Sampling Strategies  L. Lee Dupuis, Cathryn Sibbald,

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1 IV Busulfan Dose Individualization in Children undergoing Hematopoietic Stem Cell Transplant: Limited Sampling Strategies  L. Lee Dupuis, Cathryn Sibbald, Tal Schechter, Marc Ansari, Adam Gassas, Yves Théorêt, Nastya Kassir, Martin A. Champagne, John Doyle  Biology of Blood and Marrow Transplantation  Volume 14, Issue 5, Pages (May 2008) DOI: /j.bbmt Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Development phase: BA plots of AUC7 versus AUC predicted by each limited sampling strategy (LSS). (A) 1-sample LSS; (B) 2-sample LSS; (C) 3-sample LSS. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Validation phase: BA plots of AUC7 versus AUC predicted by each limited sampling strategy (LSS). (A) 1-point LSS; (B) 2-point LSS; (C) 3-point LSS. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions


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