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Breast Cancer: Alternative vs. Conventional Treatment

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1 Breast Cancer: Alternative vs. Conventional Treatment
Healing Pathways Medical Clinic Andrew Dickens NMD 6939 E. Main St. Scottsdale AZ 85251

2 Mortality in 1950: 193.9/100,000 and in 2002 193.4 per 100,000
Two of every five Americans will develop cancer (A). Most adult cancer patients today live no longer than those who had it in 1920 (B). Treatments produce the same length of life, but when you modify your lifestyle, you may live longer (C). From: Charles B. Simone, M.MS., M.D. is an Internist (Cleveland Clinic ), Medical Oncologist (National Cancer Institute ), Tumor Immunologist (NCI ), and Radiation Oncologist (University of Pennsylvania ), and is the Founder of the Simone Protective Cancer Institute (1980).  Mortality in 1950: 193.9/100,000 and in per 100,000

3 Clin Oncol 2004 Dec; 16(8):

4 Cancer remains the second leading killer in most Western industrialized nations and has crept from an incidence rate of around 1 in 500 in 1900 to 1 in 2 to 3 today. In the last 30 years there has been an 80% increase in breast cancer now 1 in 8, a 100% increase in prostate cancer, an overall increase of 49% cancer incidence in men and 41% in women. Embodied in these facts are 2 key realities. Firstly, we are not treating cancer effectively and second, we are not preventing it. Survival: Relative rates vs Absolute rates 0.5 rate increased to 0.75 is a 50% rate (relative) increase but is it really worth the cost and suffering of 0.25% better rate (absolute)?

5 Barat B. Argarwhal PhD M D Anderson Cancer Center Professor of Cancer Medicine
Cancer Causes: 30% tobacco 35% diet (70% in colorectal) 14-20% obesity 18% infections 7% e pollution and radiation 5-10% genes (and guess where the money is going)

6 Cancer Prevention and Nutrition
A review of 172 case-controlled prospective studies, comparing low verses high quartile of food consumption, showed that low fruit and vegetable consumption resulted in double the risk of cancer for most sites. (Block et al, Nutr Cancer Inst, 1992, 18: 1-29) 150 scientists reviewed 4,500 research studies on the relationship between nutrition and cancer. They found overwhelming evidence that fruits, vegetables, and grains can prevent cancer. (Cancer Prevention Research Program, 1997) This is so important! It means that the 90% of Western populations that do not eat 5 or more portions of fruit and vegetables per day are increasing their risk of getting cancer. The risk is further compounded by addition of excess animal protein intake to this phytonutrient deficit. There is published association of animal protein intake and cancer incidence (Campbell & Campbell, 2006). This information on fruit and vegetables has led to a plethora of research on the value of anti-oxidants in cancer prevention. Dr. Nyjon Eccles, BSc, MBBS, MRCP, Ph.D.

7 Genetics and Breast Cancer
BRCA1 and BRCA2 Mutations at either site carries a 70% probability of breast or ovarian cancer. BUT 95% of the time breast cancer occurs without this mutation.

8 Every year nearly 40,000 women die of breast cancer
Every year 315,000 die of heart disease Most breast cancers occur in women who are not on any hormones but are postmenopausal Post menopause brings inflammatory changes for 5-10 years

9 Women’s Health Initiative
Started 1991 with 162,000 women Several arms including: a. Oral synthetic estrogen/progestin (Prempro) b. Oral synthetic estrogen (Premarin) c. Vit D and bone health Average age was 63 (window missed) and could not have any symptoms 50% were or had been smokers Poor hormone choice and route. Oral Prempro. No attention paid to down stream metabolites

10 Women’s Health Initiative
. Oral synthetic estrogen/progestin: stopped for breast cancer increase in 4th and 5th year and also increased CHD and stroke . Oral synthetic estrogen: stopped for increase in VTE and stroke Breast cancer rates were lower

11 WHI Relative Risk WHI (CEE+MPA) RR for breast cancer 1.26
Obesity and breast cancer 1.8 to 2.99 Lung cancer from marriage to smoker 1.2 to 1.3 Smoking and lung cancer (50% of WHI) 23.2

12 Nurses’ Health Study Estrogen Dose (CEE) Age adjusted RR Never used
1.0 0.3 mg 0.43 0.625 mg 1.11 1.25 mg 1.58 Grodstein F et al, Ann. Int. Med 2000,133,

13 Breast Cancer Biological Markers
Not always present Not accurate but useful Relatively inexpensive Breast Cancer: Ca % correlation Ca 15-3 old marker 40% correlation Urokinase Plasminogen Activator (uPA) and Plasminogen Activator Inhibitor (PAI-1) Ki-67 Labeling Index Carcinembryonic Antigen (CEA) These are not tumor marker tests, but are important in making decisions about treatment. Estrogen (ER) and Progesterone Receptors (PR) Human Epidermal Growth Factor Receptor 2 (HER2/neu)

14 Scans CT scans MRI Bone scans Liver scans Brain scans
PET scans (establishes a baseline) Surgical candidate if no metastatic spread

15 Scans Digital Infrared Thermographic Imaging (DITI)
Infrared impulses detected up to 6 mm under the skin Identify symmetrical changes bilaterally (asymmetrical changes indicate pathology) DITI most helpful when correlated to a PET scan

16 Dental Assessment

17 Dental Assessment Mercury fillings (euphemistically silver fillings)
Root canals Especially #’s 2-5; ; 20,21; 28,29 Root Canal Cover-up by George Meinig DDS Cavitations Galvanic currents in the mouth Size, location, and number of dental treatments is important Electrodermal screening (EDS) is important to assess relevance Biologic dentist most helpful

18 Dental Assessment Patient Comment
I began treatments to remove my mercury fillings in 8/99 and was done by 12/99. My energy levels are much improved. My mental abilities are improved. I have more memory, clarity, and improved cognitive reasoning skills. In the past 13 months, I have been focusing on healing my body and spirit after my treatments from breast cancer. If I were to tell “my story” to a group of cancer patients and offer a check list of essential steps to heal themselves, removing heavy metals (mercury) would be top on the list. DC

19 Cancer and Emotions Address emotional and psychological causes and suppression of healing Family counseling may be necessary Forgiveness of people who wronged you Some cancers may be a latent “anger” even through family transfer from prior generations New German Medicine Ryke Hamer MD (mind/body connection) Holding babies as a volunteer in a nursery as a treatment is effective

20 Surgery Curative offered if primary
Almost never curative as by 2mm there are likely metastases Debulking adjunctive with other therapies Post protocol debulking of tumor with BioImmune protocol offered here should be considered

21 Radiation TWO EDGED SWORD - Can debulk
Increases risk of developing cancer in the future

22 Chemotherapy As much as 85% of an oncology practice income is from chemo drugs. $100 billion a year industry Really works in three cancer types: Childhood leukemia's Some lymphomas Testicular cancer Ulrich Abel, a German mathematician hired by the German government to research effectiveness of chemotherapy found it to be in one word “appalling”. Article from Der Spiegel, 33/1990, (Translation provided by People Against Cancer, Otho, Iowa).

23 Chemo Effectiveness A panel of cancer experts has ruled for a second time that Avastin, the best-selling cancer drug in the world, should no longer be used in breast cancer patients. In three unanimous votes, the six members of the FDA oncology drug panel voted that Avastin is ineffective, unsafe and should have its approval for breast cancer withdrawn. Cost: $88,000 per year with no effect. $88,000 times 40,000 breast cancer cases = loss of $3,520,000,000 potential dollars at stake.

24 Chemo Effectiveness Immediately after the final vote, patients in the audience erupted in shouts against the FDA and its panelists. "What do you want us to take!? We have nothing else!" shouted Christi Turnage, of Madison, Miss. Associated Press updated 6/29/2011 4:03:37 PM ET Insanity: doing the same thing over and over again and expecting different results. Attributed to Albert Einstein

25 Chemo Effectiveness $93,000 and prolongs life by 16 weeks
In the Journal of Clinical Oncology, the researchers report that the vaccine Provenge did not cause any serious side effects and appeared to help at least one patient. UCSF trial "We saw a partial response, meaning a reduction in the size of tumor area in one patient that was certainly attributable to the treatment,“ Dr. John Park said in a telephone interview. In three other women, their cancer appeared to stabilize for as long as a year, something that could have been due to treatment, Park said. $93,000 and prolongs life by 16 weeks


27 BioImmune Protocol IV’s Oral products Hyperthermia
Anti-angiogenic products Debulking potentially needed for rapidly necrosing tumors Coffee enemas Lymphatic stimulus Low dose naltrexone

28 Ninety Percent Reduction in Cancer Mortality after Chelation Therapy With EDTA
ABSTRACT Mortality from cancer was reduced 90% during an 18-year follow up of 59 patients treated with calcium-EDTA. Only one of 59 treated patients (1.7%) died of cancer while 30 of 172 non-treated control subjects (17.6%) died of cancer (P=0.002). Journal of Advancement in Medicine Volume 2, Numbers 1/2, Spring/Summer 1989 Walter Blumer, M.D. and Elmer Cranton, M.D.

29 Marked elevation of myocardial trace elements in idiopathic dilated cardiomyopathy compared with secondary cardiac dysfunction. A large increase (>10,000 times for mercury and antimony) of TE concentration has been observed in myocardial but not in muscular samples in all pts with IDCM. Patients with secondary cardiac dysfunction had mild increase (5 times) of myocardial TE and normal muscular TE. In particular, in pts with IDCM mean mercury concentration was 22,000 times (178,400 ng/g vs. 8 ng/g). Journal of the American College of Cardiology 1999 Volume 33, Issue 6, Pages

30 Alkaline Water Hiromi Shinya MD at Albert Einstein
Co-developer of the colonoscopy technique Performed more than 140,000 polypectomies All of his patients that he has put on a high alkaline diet with a minimum of one gallon of high alkaline water (Kangen) has had ZERO recurrence of ANY kind of cancer

31 Low Dose Naltrexone (4.5 mg)
By inducing increases of metenkephalin (an endorphin produced in large amounts in the adrenal medulla) and beta endorphin in the blood stream; By inducing an increase in the number and density of opiate receptors on the tumor cell membranes, thereby making them more responsive to the growth-inhibiting effects of the already-present levels of endorphins, which induce apoptosis (cell death) in the cancer cells; and By increasing the natural killer (NK) cell numbers and NK cell activity and lymphocyte activated CD8 numbers, which are quite responsive to increased levels of endorphins. Irmat pharmacy carries a biologically active form as potentially opposed to many others.

32 Medicinal Mushrooms Coriolus versicolor, the extract PSK is the best selling alternative anticancer drug in the world. The BioImmune protocol uses “Immune Option” that includes 7 medicinal mushrooms with other synergistic nutrients Breast cancer Patients who added PSK to their chemotherapy treatment had an 81 per cent survival rate after 10 years, compared to patients on chemotherapy alone, who had a 65 per cent survival rate4. However, breast cancer patients identified as having the HLA-B40 antigen had a much better result. HLA-B40-positive patients who added PSK to their treatment had a 100 per cent survival rate after 10 years, compared with 55 per cent survival rate for chemotherapy alone Yokoe et al. Anticancer Research, 1997

33 Diet Max Gerson MD said the most important thing is to restore the liver cellular generations and that is 1 ½ years Cancer as a degenerative/deficiency disease and need to restore/refill the liver to detox body Potassium is the mineral of need. Why Gerson diet worked (alkaline, in Na/K pump inhibits replication, needed in Kreb cycle) oxidizing Relief of severe pain was achieved in about 90 percent of cases." Medical Hypotheses, 7, 1981, pp

34 Diet Raw foods have much potassium No sodium allowed
Some very lightly steamed veggies are ok Must avoid acidic foods: meat, alcohol, etc Organic best (no pesticides, etc to further poison the liver and reduce detoxification) and higher in nutrition Avoidance of animal proteins Low caloric value Snickers vs apple Nutrition dense vs caloric dense Juices have to be made in explicit juicers Supplementation critical

35 Protective Supplements
Joseph McWherter MD a Gyn in Ft Worth has treated over 3,000 women in the age group of 40’s to the 60’s (average of 3 yrs) By using thyroid, high dose fish oil, MVI, and BioImmune “Breast Protect” with he has only one case of breast cancer (vs 1 in 8 lifetime). Great for all age groups.

36 Fibrinolytic Enzymes Helps with digestion of dead tumor mass
Taken away from meals, fibrinolytic enzymes break down the cellular covering that hides a cancer cell from the immune system. Boluoke great product. - Dr John Beard in Scotland The Unitarian Trophoblastic Theory of cancer in 1902. - Further Developed by Donald Kelly DDS Nicholas Gonzalez MD currently in NY

37 Coffee Enemas Karate Kid: Pat Morita and Ralph Macchio with the “guess so” quote. “Like grape-squish.” Max Gerson MD. First used by Prof O A Meyer in Goettingen for bile flow increase –the “Why”. 3 heaping tbs in one qt water, boil for three minutes, simmer for and give when at body temperature. Reduces/stops pain if given every one to two hours instead of usual 4 hrs. Stop pain meds potentially esp if 3-4 o’clock am enema given Detoxification for liver

38 Hyperthermia Thermal carcinolysis > 103F
Inhibition of microcirculation in cancer tissue Induces hyperglycemia and overacidification to the extent that the cancer cells, as facultative anaerobes, sustain damaged cellular or organelle membranes Fat thermolysis and subsequent toxin removal HSP increase NK increase

39 BioImmune Protocol Vitamin C (Corn-Source) -5.0% 5-FU 38.0%
Agent Used   Decrease in Cancer Growth Vitamin C (Corn-Source) % 5-FU % 5-FU + Vitamin C % X rays (Radiation) % X rays + Vitamin C % Bleomycin % Bleomycin + Vitamin C %  Source: Kedar Prasad, University of Colorado, as summarized in Antioxidants Against Cancer by Ralph Moss

40 BioImmune Protocol Comparison of Corn-Source and Non-Corn Source, Full Levorotatory Vitamin-C K562 Erythroleukemic Cells (Human Leukemia Cancer cells) Control (negative-cell growth media) to 9 % Control (positive-Camptothecin) % Corn Source Vitamin-C % (5 mcg/ml media concentration) (Non Corn-Source Vitamin-C) % Full levorotary Vit C demonstrates 4-times the selective killing of human leukemia Cancer Cells in a laboratory study, compared to normal intravenous corn-derived Vitamin-C.

41 BioImmune Protocol Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues. PNAS Sept 20,2005; Mark Levine MD, Center for Drug Evaluation and Research, FDA Cancer cells lack catalase and glutathione peroxidase to protect themselves from the oxidative effects of high dose Vit C

42 Cancer and CoQ10 Although CoQ10 is best documented in the treatment of heart failure, two medical journal articles suggest tremendous promise in the treatment of cancer. Folkers (1997) described 10 cancer patients given CoQ10 for heart failure. One of the patients, a 48-year-old man diagnosed with inoperable lung cancer, had no signs of either cancer or heart failure symptoms while taking CoQ10 for 17 years. Folkers K, Osterborg A, Nylander M, Morita M, Mellstedt H. Activities of vitamin Q10 in animal models and a serious deficiency in patients with cancer. Biochem Biophys Res Commun. 1997;234(2):

43 CoQ10 and Cancer Knud Lockwood, M.D (1994), a cancer specialist in Copenhagen, Denmark, described his treatment of 32 "high-risk" breast cancer patients with antioxidant vitamins, essential fatty acids, and CoQ10. "No patient died and all expressed a feeling of well-being," he wrote "These clinical results are remarkable …..After 24 months, all still survived; about 6 deaths would have been expected." Lockwood, who has apparently treated some 7,000 cases of breast cancer over 35 years, wrote that until using CoQ10, he had "never seen a spontaneous complete regression of a centimeter breast tumor, and has never seen a comparable regression on any conventional anti-tumor therapy." Dr. Nyjon Eccles, BSc, MBBS, MRCP, Ph.D. HPMC carries Idebenone, a better assimilated BioImmune product

44 BioImmune Protocol Objective
To determine if a nutraceutical regimen alone can significantly increase survival and decrease symptoms in patients with recurrent and/or late stage cancers and immune diseases.

45 BioImmune Protocol Methods and Side Effects
Oral and I.V. nutraceuticals were administered. Traditional monitoring was utilized: blood test and tumor markers, ultrasound, CAT and PET scans and physical exams. The only toxicity noted was occasional diarrhea and nausea at the inception of the protocols.

46 BioImmune Protocol Case Studies
Patients: After informed consent was obtained: 9 patients were evaluated: a. 1 Breast Cancer Stage IV reoccurrence after 2 stem cell transplant failures with metastasis to pancreas, liver, skull, lungs and abdominal lining b. 1 Follicular Lymphoma Stage II : 8-tumors in head

47 BioImmune Protocol Case Studies
c. 1 Stage IV Colon/Rectal Cancer with metastasis to liver and lymph nodes d. 1 Stage IV Inflammatory Breast Cancer with metastasis to lungs and virtually everywhere in skeletal system; resistant to surgery, chemo and radiation/hyperthermia combinations. Failed local IPT. e. 1 Stage IV Esophageal Squamous Cell after failed treatments consisting of radical neck dissection surgery, chemo and radiation: gray countenance and dying

48 BioImmune Protocol Case Studies
f. 1 Stage IV Burkett’s Lymphoma with an orange-size mass under chin and skeletal bone biopsies indicating 70% of bone marrow cancerous; given days to live g. 1 Stage IV Renal Cell Cancer with metastasis to skeletal system and both lobes of the lungs; given 10 days to live with a further complication of Advanced Hepatitis-C h. l Stage IV AML Leukemia in Blast Crisis, given 12 days to live. Gray countenance and dying hourly

49 BioImmune Protocol Case Studies
i. 1 Stage IV primary Thyroid Cancer Metastatic, complicated with primary Renal Cell Cancer and CLL Leukemia. Patient was given 3 ½ weeks to live. j. Stage IV primary Prostate Cancer with metastasis to skeletal system. Biopsy revealed the cancer was the most aggressive form. Patient was given less than 1 year to live. k. Stage IV primary Pancreatic Cancer with spread to liver after Whipple Surgery. Patient was given only a few months to live.

50 BioImmune Protocol Case Studies
Breast Cancer Stage 4 a. 5/ yr. old female diagnosed w/reoccurance of Breast Cancer 4 ½ months after 2 stem cell back to back bone marrow transplants. metastasis to skull, abdominal lining, lungs, pancreas, & liver 6/95 initiated an aggressive oral nutraceutical program 8/95 CAT & bone scans indicate absence of all tumors

51 BioImmune Protocol Case Studies
d. 4/01 37 yr. old female diagnosed w/ Inflammatory Breast Cancer w/mets to virtually everywhere in skeletal system 4/01 to 6/02 chemo followed by radiation and hyperthermia with nominal success on old tumors & new tumors appearing weekly 6/02 Initiated oral & I.V. program 8/02 Scans & physical exams in France found no tumors anywhere, bone pain totally gone!

52 BioImmune Protocol Case Studies
Follicular Lymphoma Stage 2C & B-cell Lymphoma Cancers: 8 Tumors in Head b. 9/01 54 yr old male diagnosed with 8 tumors in head with the largest being golf ball size. Patient initiated oral program 10/01 PET & CAT Scan revealed all masses except right neck mass was gone. Neck mass rapidly shrinking and reduced to 1.2 cm 10/03 Patient still in full remission & feeling great

53 BioImmune Nutraceuticals
Intravenous (50 to 100 gm/day) Cassava (non-corn) derived L-ascorbic acid; other IV products as indicated; oral Immune Response Enhanced (a combination of vitamin, minerals, antioxidants, immune modulating and enhancing natural products; oral Ultra Absorbic-C, (Microsphere encapsulated Cassava derived vitamin-C), DeTox Max Plus, undenatured whey protein, enzymes, and other oral nutraceuticals and IV products were used for specific cancers.

54 BioImmune Protocol Case Studies
Conclusion: All 11 patients responded and achieved remission. An aggressive combination of immune active oral and intravenous nutraceuticals was effective in significantly improving the outcome of late stage cancers, resulting in enhanced longevity and increased quality of life. Nutraceutical protocols can be effective in a broad spectrum of late stage cancers.

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