1. Volume 366, Issue 9503, Pages 2087-2106 (December 2005)
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials 
The Lancet 
Volume 366, Issue 9503, Pages (December 2005)
DOI: /S (05)
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2. Figure 1
Effect of radiotherapy (RT) after BCS (ten trials) on local recurrence and on breast cancer mortality—event rate ratios
O–E=observed–expected. BW=breast/chest wall. S=scar (as site of RT boost). AF=axilla/fossa. IMC=internal mammary chain. Sites in parentheses not always treated.
*Some systemic adjuvant therapy (same polychemotherapy and/or tamoxifen) in both groups.
99% CIs are given for trial-specific results (black squares) and 95% CIs are given for subtotals and totals (white diamonds).
The Lancet  , DOI: ( /S (05) )
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3. Figure 2
Effect of radiotherapy (RT) after BCS on local recurrence and on breast cancer mortality—15-year probabilities
Data from 10 trials. Vertical lines indicate 1 SE above or below the 5, 10, and 15 year percentages.
The Lancet  , DOI: ( /S (05) )
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4. Figure 3
Effect of radiotherapy (RT) after mastectomy and axillary clearance (AC) on local recurrence and on breast cancer mortality—15-year probabilities
Data from 25 trials. Vertical lines indicate 1 SE above or below the 5, 10, and 15 year percentages.
The Lancet  , DOI: ( /S (05) )
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5. Figure 4
Absolute reduction in 5-year local recurrence risk—78 randomised comparisons grouped into 24 types of local treatment comparison, based on treatments compared and nodal status
RT=radiotherapy. AC=axillary clearance. AS=axillary sampling. IMC=internal mammary chain of lymph nodes.
*A few trials did not provide data on local recurrence, so in some comparisons numbers differ from table 1.
The Lancet  , DOI: ( /S (05) )
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6. Figure 5
Local recurrence and breast cancer mortality for treatment comparisons that produce a less than 10% (upper panels) or more than 10% (lower panels) absolute reduction in 5-year local recurrence risk—15-year probabilities
Vertical lines indicate 1 SE above or below the 5, 10, and 15 year percentages.
The Lancet  , DOI: ( /S (05) )
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7. Figure 6
Effect of radiotherapy (RT) on breast cancer mortality and on all-cause mortality after BCS or after mastectomy with axillary clearance (AC)—15-year or 20-year probabilities
Vertical lines indicate 1 SE above or below the 5, 10, and 15 year percentages.
The Lancet  , DOI: ( /S (05) )
Copyright © 2005 Elsevier Ltd Terms and Conditions