1. Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care

2. Global Burden of VTE

3. Global Burden of VTE (cont)

4. Thrombosis UK

5. Virchow's Triad

6. Thrombosis in Medical Patients

7. Other Contributing Factors

8. Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care

9. Patients at Risk for VTE: Surgical Patients

10. Patients at Risk for VTE: Medical Patients

11. Patients at Risk for VTE: Other Factors

12. Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care

13. Patients at Risk for VTE

14. Multi-Disciplinary Approach

15. Electronic Alerts Reduce VTE

16. Thromboprophylaxis

17. Non-Pharmacologic Prophylaxis

18. Pharmacologic Prophylaxis

19. Summary

20. Summary (cont)

21. Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care

22. Trials of VTE Prophylaxis in Hospitalized Medical Patients

23. Previous Studies of Extended Thromboprophylaxis in Acute Medically Ill Patients

24. APEX Study Design

25. MAGELLAN D-Dimer

26. APEX Results

27. APEX Net Clinical Benefit (VTE or Major Bleed)

28. APEX Dose Reduction

29. Betrixaban FDA Approval

30. MARINER Trial Medical Patients at High Risk of VTE

31. MARINER vs APEX

32. Summary

33. Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care

34. VTE Risk After Discharge

35. VTE Risk Remains After Discharge

36. Improving Patient Outcomes

37. Abbreviations