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Qingping Yao, MD, PhD, Bo Shen, MD  The American Journal of Medicine 

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Presentation on theme: "Qingping Yao, MD, PhD, Bo Shen, MD  The American Journal of Medicine "— Presentation transcript:

1 A Systematic Analysis of Treatment and Outcomes of NOD2-Associated Autoinflammatory Disease 
Qingping Yao, MD, PhD, Bo Shen, MD  The American Journal of Medicine  Volume 130, Issue 3, Pages 365.e e18 (March 2017) DOI: /j.amjmed Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure Rash and leg swelling occur in Yao syndrome patients. Erythematous patches and plaques are observed on the chest in (A) and on the face and forehead in (B); spongiotic dermatitis is present (hematoxylin & eosin stain, 20×), demonstrating irregular epidermal hyperplasia with spongiosis with overlying hyperkeratosis and parakeratosis. There is superficial perivascular lymphocytic infiltrate in (C), and distal extremity nonpitting swelling can appear, lasting a few days to weeks, usually associated with arthralgia and rash in (D). The American Journal of Medicine  , 365.e e18DOI: ( /j.amjmed ) Copyright © 2016 Elsevier Inc. Terms and Conditions


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